Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B (jmjd6-b) Recombinant Protein | jmjd6-b recombinant protein
Recombinant Xenopus laevis Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B (jmjd6-b)
Gene Names
jmjd6.S; psr; jmjd6; ptdsr; cg5383; ptdsr1; jmjd6-a; jmjd6-b
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B (jmjd6-b); Recombinant Xenopus laevis Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B (jmjd6-b); jmjd6-b recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-403, Full length protein
Sequence
MNHKSKKRIKEAKRSARPELKDSQDWCRHNYCEVFSLNPSTVLDNVERVDAAQLTTEEFIERYEKPYKPVVIINATAGWPANEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYIDYMEGTRDDSPLYIFDSSYGEHPKRKKILEDYEVPKYFRDDLFQFTGEKRRPPYRWFVMGPPRSGTGIHIDPLGTSAWNSLVHGHKRWCLFPTNTPRELIKVTRDEGGNQQDEAITWFNVVYPRTQLPSWPPEFKPLEILQKPGETVFVPGGWWHVVLNFDTAIAVTQNFASCSNFPVVWHKTVRGRPKLSRKWYRILKQERPELAALADTVDLQESTGIASDSSSDSSSSSSSSSSESCSEDDSSSGAEMMSRRKKKRRLCNGMGNGDITTQDDCASKERSSSR
Sequence Length
403
Species
Xenopus laevis (African clawed frog)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,516 Da
NCBI Official Full Name
bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B
NCBI Official Synonym Full Names
jumonji domain containing 6 S homeolog
NCBI Official Symbol
jmjd6.S
NCBI Official Synonym Symbols
psr; jmjd6; ptdsr; cg5383; ptdsr1; jmjd6-a; jmjd6-b
NCBI Protein Information
bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B
UniProt Protein Name
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B
Protein Family
UniProt Gene Name
jmjd6-b
UniProt Synonym Gene Names
ptdsr-b; Protein PTDSR-B
Uniprot Description
Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as u2af2/u2af65. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of u2af2/u2af65, affecting the pre-mRNA splicing activity of u2af2/u2af65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. However, histone arginine demethylation may not constitute the primary activity in vivo. Has no histone lysine demethylase activity. Required for differentiation of multiple organs during embryogenesis. Acts as a key regulator of hematopoietic differentiation ().
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Product Notes
The jmjd6-b jmjd6-b (Catalog #AAA1460833) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-403, Full length protein. The amino acid sequence is listed below: MNHKSKKRIK EAKRSARPEL KDSQDWCRHN YCEVFSLNPS TVLDNVERVD AAQLTTEEFI ERYEKPYKPV VIINATAGWP ANEKWTLERL KRKYRNQKFK CGEDNDGYSV KMKMKYYIDY MEGTRDDSPL YIFDSSYGEH PKRKKILEDY EVPKYFRDDL FQFTGEKRRP PYRWFVMGPP RSGTGIHIDP LGTSAWNSLV HGHKRWCLFP TNTPRELIKV TRDEGGNQQD EAITWFNVVY PRTQLPSWPP EFKPLEILQK PGETVFVPGG WWHVVLNFDT AIAVTQNFAS CSNFPVVWHK TVRGRPKLSR KWYRILKQER PELAALADTV DLQESTGIAS DSSSDSSSSS SSSSSESCSE DDSSSGAEMM SRRKKKRRLC NGMGNGDITT QDDCASKERS SSR. It is sometimes possible for the material contained within the vial of "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6-B (jmjd6-b), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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