Ribosomal Protein L22 Recombinant Protein | RPL22 recombinant protein

Recombinant Human Ribosomal Protein L22

Cat. Num. AAA145730

• Gene Names: RPL22; EAP; L22; HBP15; HBP15/L22
• Purity: Greater than 85% as determined by SDS-PAGE.
• Synonyms: Ribosomal Protein L22; Recombinant Human Ribosomal Protein L22; RPL22 Human; Ribosomal Protein L22 Human Recombinant; Heparin-Binding Protein HBp15; Epstein-Barr-Encoded RNA-Associated Protein; Epstein-Barr Virus Small RNA-Associated Protein; 60S Ribosomal Protein L22; EBER-Associated Protein; EAP; HBP15/L22; RPL22 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 85% as determined by SDS-PAGE.
• Form/Format: The RPL22 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 20% glycerol.; Sterile Filtered clear solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAPVKKL VVKGGKKKKQ VLKFTLDCTH PVEDGIMDAA NFEQFLQERI KVNGKAGNLG GGVVTIERSK SKITVTSEVP FSKRYLKYLT KKYLKKNNLR DWLRVVANSK ESYELRYFQI NQDEEEEEDE D
• Sequence Length: 128

Related Product Information for RPL22 recombinant protein

Description: RPL22 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 151 amino acids (1-128) and having a molecular mass of 17.0kDa.RPL22 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: RPL22, a cytoplasmic ribosomal protein, is a member of the L22E family of ribosomal proteins and a component of the 60S subunit. RPL22 binds specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2.

Product Categories/Family for RPL22 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Ribosomal Protein

NCBI and Uniprot Product Information

• NCBI GI #: 4506613
• NCBI GeneID: 6146
• NCBI Accession #: NP_000974.1
• NCBI GenBank Nucleotide #: NM_000983.3
• UniProt Accession #: P35268; Q6IBD1; B2R495
• Molecular Weight: 14,787 Da
• NCBI Official Full Name: 60S ribosomal protein L22 proprotein
• NCBI Official Synonym Full Names: ribosomal protein L22
• NCBI Official Symbol: RPL22
• NCBI Official Synonym Symbols: EAP; L22; HBP15; HBP15/L22
• NCBI Protein Information: 60S ribosomal protein L22; EBER-associated protein; Epstein-Barr virus small RNA-associated protein; Epstein-Barr-encoded RNA-associated protein; heparin-binding protein 15; heparin-binding protein HBp15
• UniProt Protein Name: 60S ribosomal protein L22
• Protein Family: 50S ribosomal protein
• UniProt Gene Name: RPL22
• UniProt Synonym Gene Names: EAP
• UniProt Entry Name: RL22_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2. [provided by RefSeq, Jul 2008]

Uniprot Description

RPL22: a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2. [provided by RefSeq, Jul 2008]

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 1p36.31

Cellular Component: focal adhesion; cytoplasm; cytosol; ribonucleoprotein complex; nucleus

Molecular Function: heparin binding; protein binding; structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; translational elongation; cellular protein metabolic process; viral reproduction; translation; mRNA catabolic process, nonsense-mediated decay; translational initiation; alpha-beta T cell differentiation; viral transcription; gene expression; viral infectious cycle; translational termination