Fatty Acid Amide Hydrolase 2 Recombinant Protein | FAAH2 recombinant protein

Recombinant Human Fatty Acid Amide Hydrolase 2

Cat. Num. AAA145685

• Gene Names: FAAH2; AMDD
• Purity: Greater than 80% as determined by SDS-PAGE.
• Synonyms: Fatty Acid Amide Hydrolase 2; Recombinant Human Fatty Acid Amide Hydrolase 2; FAAH2 Human; Fatty Acid Amide Hydrolase 2 Human Recombinant; Fatty acid amide hydrolase 2; AMDD; Amidase domain-containing protein; Anandamide amidohydrolase 2; Oleamide hydrolase 2; FAAH2; FAAH2 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 80% as determined by SDS-PAGE.
• Form/Format: The FAAH2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M Urea.; Sterile Filtered clear solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MGSGGPKFAS KTPRPVTEPL LLLSGMQLAK LIRQRKVKCI DVVQAYINRI KDVNPMINGI VKYRFEEAMK EAHAVDQKLA EKQEDEATLE NKWPFLGVPL TVKEAFQLQG MPNSSGLMNR RDAIAKTDAT VVALLKGAGA IPLGITNCSE LCMWYESSNK IYGRSNNPYD LQHIVGGSSG GEGCTLAAAC SVIGVGSDIG GSIRMPAFFN GIFGHKPSPG VVPNKGQFPL AVGAQELFLC TGPMCRYAED LAPMLKVMAG PGIKRLKLDT KVHLKDLKFY WMEHDGGSFL MSKVDQDLIM TQKKVVVHLE TILGASVQHV KLKKMKYSFQ LWIAMMSAKG HDGKEPVKFV DLLGDHGKHV SPLWELIKWC LGLSVYTIPS IGLALLEEKL RYSNEKYQKF KAVEESLRKE LVDMLGDDGV FLYPSHPTVA PKHHVPLTRP FNFAYTGVFS ALGLPVTQCP LGLNAKGLPL GIQVVAGPFN DHLTLAVAQY LEKTFGGWVC PGKF
• Sequence Length: 532

• Physical Appearance: Sterile Filtered clear solution.
• Preparation and Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.; For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).; Avoid multiple freeze-thaw cycles.

Related Product Information for FAAH2 recombinant protein

FAAH2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 524 amino acids (32-532a.a) and having a molecular mass of 57.4kDa. FAAH2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Categories/Family for FAAH2 recombinant protein

Enzymes; Hydrolase

NCBI and Uniprot Product Information

• NCBI GI #: 195972892
• NCBI GeneID: 158584
• NCBI Accession #: NP_777572.2
• NCBI GenBank Nucleotide #: NM_174912.3
• UniProt Accession #: Q6GMR7; Q86VT2; Q96N98
• NCBI Official Full Name: fatty-acid amide hydrolase 2
• NCBI Official Synonym Full Names: fatty acid amide hydrolase 2
• NCBI Official Symbol: FAAH2
• NCBI Official Synonym Symbols: AMDD
• NCBI Protein Information: fatty-acid amide hydrolase 2; amidase domain containing; amidase domain-containing protein; anandamide amidohydrolase 2; oleamide hydrolase 2
• UniProt Protein Name: Fatty-acid amide hydrolase 2
• Protein Family: Fatty-acid amide hydrolase
• UniProt Gene Name: FAAH2
• UniProt Synonym Gene Names: AMDD
• UniProt Entry Name: FAAH2_HUMAN

NCBI Description

This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate.[provided by RefSeq, Sep 2009]

Uniprot Description

FAAH2: Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. Belongs to the amidase family.

Protein type: EC 3.5.1.99; Hydrolase; Membrane protein, integral

Chromosomal Location of Human Ortholog: Xp11.21

Cellular Component: integral to membrane

Molecular Function: carbon-nitrogen ligase activity, with glutamine as amido-N-donor; hydrolase activity

Biological Process: metabolic process