Prolactin-Induced Protein | PIP protein
Human Prolactin-Induced Protein
Gene Names
PIP; GPIP4; GCDFP15; GCDFP-15
Purity
Greater than 95% as determined by SDS-PAGE.
Synonyms
Prolactin-Induced; Human Prolactin-Induced Protein; PIP Human; Prolactin-Induced Protein Human; Prolactin-inducible protein; Gross cystic disease fluid protein 15; GCDFP-15; Prolactin-induced protein; Secretory actin-binding protein; SABP; gp17; PIP; GCDFP15; GPIP4; PIP protein
Host
Human Seminal Plasma
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
PIP protein filtered (0.4 um) and lyophilized in 0.5mg/ml in 0.05M phosphate buffer and 0.075M NaCl pH 8.0.
Filtered White lyophilized (freeze-dried) powder.
Filtered White lyophilized (freeze-dried) powder.
Sequence
QDNTRKIIIK NFDIPKSVRP NDEVTAVLAV QTELKECMVV KTYLISSIPL QGAFNYKYTA CLCDDNPKTF YWDFYTNRTV QIAAVVDVIR ELGICPDDAA VIPIKNNRFY TIEILKVE
Sequence Length
146
Solubility
It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. PIP is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Human Virus Test
Samples from each donor have been tested and found negative for HBsAg, HIV1+2, HCV, syphilis, aHBc, RRR.
Preparation and Storage
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4° for a limited period of time; it does not show any change after two weeks at 4°C.
Related Product Information for PIP protein
Description: The Prolactin-Induced Protein produced from Human Seminal Plasma has a molecular mass of 13.52kDa (calculated without glycosylation) containing 118 amino acid residues.
Introduction: Prolactin inducible protein (PIP) is a 17kDa glycoprotein existing in human seminal plasma. PIP is synthesized as a 146 amino acid long polypeptide exhibiting high sequence similarity with mouse submaxillary gland with a single glycosylation site. The precise biological functions of PIP are still ambiguous but various functions have been assigned to PIP due its existence at high concentration in biological fluids. PIP binds to various proteins such as fibrinogen, actin, keratin, myosin and tropomyosin. PIP is also expressed in pathological conditions of the mammary gland and in some exocrine tissues, such as the lacrimal, salivary and sweat glands. Due to PIP's association with secretory cell differentiation, it has been used in evaluation of tumors of breast, salivary gland, and skin.
Introduction: Prolactin inducible protein (PIP) is a 17kDa glycoprotein existing in human seminal plasma. PIP is synthesized as a 146 amino acid long polypeptide exhibiting high sequence similarity with mouse submaxillary gland with a single glycosylation site. The precise biological functions of PIP are still ambiguous but various functions have been assigned to PIP due its existence at high concentration in biological fluids. PIP binds to various proteins such as fibrinogen, actin, keratin, myosin and tropomyosin. PIP is also expressed in pathological conditions of the mammary gland and in some exocrine tissues, such as the lacrimal, salivary and sweat glands. Due to PIP's association with secretory cell differentiation, it has been used in evaluation of tumors of breast, salivary gland, and skin.
Product Categories/Family for PIP protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,572 Da
NCBI Official Full Name
prolactin-inducible protein
NCBI Official Synonym Full Names
prolactin-induced protein
NCBI Official Symbol
PIP
NCBI Official Synonym Symbols
GPIP4; GCDFP15; GCDFP-15
NCBI Protein Information
prolactin-inducible protein; SABP; gross cystic disease fluid protein 15; secretory actin-binding protein
UniProt Protein Name
Prolactin-inducible protein
Protein Family
UniProt Gene Name
PIP
UniProt Synonym Gene Names
GCDFP15; GPIP4; GCDFP-15; SABP
UniProt Entry Name
PIP_HUMAN
Uniprot Description
PIP: Belongs to the PIP family.
Protein type: Cytoskeletal; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7q34
Cellular Component: extracellular space; apical plasma membrane; nucleus
Molecular Function: protein dimerization activity; protein binding; IgG binding; actin binding; aspartic-type endopeptidase activity; glycoprotein binding
Biological Process: retinal homeostasis; regulation of immune system process; detection of chemical stimulus involved in sensory perception of bitter taste; proteolysis
Research Articles on PIP
Similar Products
Product Notes
The PIP pip (Catalog #AAA145461) is a Protein produced from Human Seminal Plasma and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: QDNTRKIIIK NFDIPKSVRP NDEVTAVLAV QTELKECMVV KTYLISSIPL QGAFNYKYTA CLCDDNPKTF YWDFYTNRTV QIAAVVDVIR ELGICPDDAA VIPIKNNRFY TIEILKVE. It is sometimes possible for the material contained within the vial of "Prolactin-Induced, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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