L-amino-acid oxidase Recombinant Protein | DRS-LAAO recombinant protein
Recombinant Daboia russelli siamensis L-amino-acid oxidase
NCBI and Uniprot Product Information
Uniprot Description
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids (highly active against L-Leu followed by L-Phe and L-Ile and not active against L-Pro, L-Asn, L-Gly, L-Ser and L-Cys), thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme. Exhibits diverse biological activities such as antibacterial activity (Minimal inhibitory concentrations (MIC) are 9.0 µg/ml against S.aureus, 144.0 µg/ml against P.aeruginosa and 288.0 µg/ml against E.coli) and inhibition of ADP- and TMVA-induced platelet aggregation. Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation. These different effects are probably due to different experimental conditions. Unlike other snake venom L-amino acid oxidases, does not induce hemorrhage. This protein may also induce hemolysis, edema, apoptosis and have antiparasitic activities.
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Product Notes
The L-amino-acid oxidase drs-laao (Catalog #AAA1453886) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-407, Full length protein. The amino acid sequence is listed below: ADDKNPLEEC FREDDHRIVR EYIRKFGLKL NEFVQETENG WYFIKNIRKR VGEVKKDPGL LKYPVKPSEA GKSAGQLYQE SLGKAVEELK RTNCSYILNK YDTYSTKEYL IKEGNLSPGA VDMIGDLLNE DSGYYVSFIE SLKHDDIFAY EKRFDEIVGG MDQLPTSMYR AIEESVRFKA RVIKIQQNAE KVTVTYQTTQ KNLLLETVDY VIVCTTSRAA RRITFKPPLP PKKAHALRSV HYRSGTKIFL TCTKKFWEDD GIQGGKSTTD LPSRFIYYPN HNFTTGVGVI IAYGIGDDAN FFQALNLNEC ADIVFNDLSS IHQLPKKDLQ TFCYPSIIQK WSLDKYAMGA ITTFTPYQFQ HFSEALTAPV GRIFFAGEYT ANAHGWIDST IKSGLTAARD VNRASEL. It is sometimes possible for the material contained within the vial of "L-amino-acid oxidase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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