Proteasome Assembly Chaperone 2 Recombinant Protein | PSMG2 recombinant protein
Recombinant Human Proteasome Assembly Chaperone 2
Gene Names
PSMG2; PAC2; HCCA3; CLAST3; MDS003; HsT1707; TNFSF5IP1
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Proteasome Assembly Chaperone 2; Recombinant Human Proteasome Assembly Chaperone 2; PSMG2 Human; Proteasome Assembly Chaperone 2 Human Recombinant; Proteasome assembly chaperone 2; PAC-2; Hepatocellular carcinoma-susceptibility protein 3; Tumor necrosis factor superfamily member 5-induced protein 1; PSMG2; HCCA3; PAC2; TNFSF5IP1; CLAST3; MDS003; HsT1707; MGC15092; PSMG2 recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
PSMG2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 40% glycerol and 0.1M NaCl.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMFVPCGE SAPDLAGFTL LMPAVSVGNV GQLAMDLIIS TLNMSKIGYF YTDCLVPMVG NNPYATTEGN STELSINAEV YSLPSRKLVA LQLRSIFIKY KSKPFCEKLL SWVKSSGCAR VIVLSSSHSY QRNDLQLRST PFRYLLTPSM QKSVQNKIKS LNWEEMEKSR CIPEIDDSEF CIRIPGGGIT KTLYDESCSK EIQMAVLLKF VSEGDNIPDA LGLVEYLNEW LQILKPLSDD PTVSASRWKI PSSWRLLFGS GLPPALF
Sequence Length
264
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for PSMG2 recombinant protein
Description: PSMG2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 287 amino acids (1-264 a.a.) and having a molecular mass of 31.8kDa.PSMG2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Proteasome assembly chaperone 2 (PSMG2) stimulates assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits and promotes compilation of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. PSMG2 is widely expressed with highest levels in the lung, brain and colon. It is moderately expressed in the muscle, stomach, spleen and heart, and weakly expressed in the small intestine, pancreas and liver. It is also highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue.
Introduction: Proteasome assembly chaperone 2 (PSMG2) stimulates assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits and promotes compilation of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. PSMG2 is widely expressed with highest levels in the lung, brain and colon. It is moderately expressed in the muscle, stomach, spleen and heart, and weakly expressed in the small intestine, pancreas and liver. It is also highly expressed in hepatocellular carcinomas with low levels in surrounding liver tissue.
Product Categories/Family for PSMG2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,321 Da
NCBI Official Full Name
proteasome assembly chaperone 2 isoform 1
NCBI Official Synonym Full Names
proteasome (prosome, macropain) assembly chaperone 2
NCBI Official Symbol
PSMG2
NCBI Official Synonym Symbols
PAC2; HCCA3; CLAST3; MDS003; HsT1707; TNFSF5IP1
NCBI Protein Information
proteasome assembly chaperone 2; CD40 ligand-activated specific transcript 3; HDCMC29P; HSPC260; PAC-2; PSMG2; hepatocellular carcinoma susceptibility protein; hepatocellular carcinoma-susceptibility protein 3; likely ortholog of mouse CD40 ligand-activated specific transcript 3 (Clast3); proteasome assembling chaperone 2; tumor necrosis factor superfamily member 5-induced protein 1; tumor necrosis factor superfamily, member 5-induced protein 1; x 003 protein
UniProt Protein Name
Proteasome assembly chaperone 2
Protein Family
UniProt Gene Name
PSMG2
UniProt Synonym Gene Names
PAC-2
UniProt Entry Name
PSMG2_HUMAN
Uniprot Description
PSMG2: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization. Belongs to the PSMG2 family.
Chromosomal Location of Human Ortholog: 18p11.21
Cellular Component: nucleus
Molecular Function: protein binding
Biological Process: mitotic cell cycle spindle assembly checkpoint; proteasome assembly; negative regulation of apoptosis
Research Articles on PSMG2
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Product Notes
The PSMG2 psmg2 (Catalog #AAA145003) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMFV PCGE SAPDLAGFTL LMPAVSVGNV GQLAMDLIIS TLNMSKIGYF YTDCLVPMVG NNPYATTEGN STELSINAEV YSLPSRKLVA LQLRSIFIKY KSKPFCEKLL SWVKSSGCAR VIVLSSSHSY QRNDLQLRST PFRYLLTPSM QKSVQNKIKS LNWEEMEKSR CIPEIDDSEF CIRIPGGGIT KTLYDESCSK EIQMAVLLKF VSEGDNIPDA LGLVEYLNEW LQILKPLSDD PTVSASRWKI PSSWRLLFGS GLPPALF. It is sometimes possible for the material contained within the vial of "Proteasome Assembly Chaperone 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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