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RAB24 recombinant protein

Recombinant Human RAB24, Member RAS Oncogene Family

Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
RAB24; Recombinant Human RAB24; Member RAS Oncogene Family; RAB24 Human; Member RAS Oncogene Family Human Recombinant; RAB24 member RAS oncogene family; ras-related protein Rab-24; RAB24 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
The RAB24 solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.1M NaCl, 0.1M EDTA and 30% glycerol.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSHMSGQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH
Sequence Length
203
Related Product Information for RAB24 recombinant protein
Description: RAB24 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 227 amino acids (1-203) and having a molecular mass of 25.7 kDa.RAB24 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: RAB24 is a member of the small GTPase superfamily which regulates intracellular protein transferring, nonetheless the specific role of RAB24 has not yet been revealed. RAB24 is distributed in the endoplasmic reticulum/cis-Golgi region and on late endosomal structures which suggests connection to autophagy-related courses. RAB24 demonstrates uncommon characteristics such as low intrinsic GTPase activity, and is incompetently prenylated when compared with other Rab proteins indicates that RAB24 has a distinctive part in the degradation of misfolded cellular proteins or trafficking of proteins to the nuclear envelope.
Product Categories/Family for RAB24 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,124 Da
NCBI Official Full Name
ras-related protein Rab-24
NCBI Official Synonym Full Names
RAB24, member RAS oncogene family
NCBI Official Symbol
RAB24
NCBI Protein Information
ras-related protein Rab-24
UniProt Protein Name
Ras-related protein Rab-24
Protein Family
UniProt Gene Name
RAB24
UniProt Entry Name
RAB24_HUMAN

NCBI Description

RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009]

Uniprot Description

RAB24: a small G protein of the Rab family. Differs from other Rab proteins in that it has a low intrinsic GTPase activity. May be involved in autophagy-related processes.

Protein type: Autophagy; G protein, monomeric; G protein; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: mitochondrion; membrane; endocytic vesicle; autophagic vacuole; cytosol; endosome

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: intracellular protein transport; autophagy; Rab protein signal transduction

Research Articles on RAB24

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Product Notes

The RAB24 rab24 (Catalog #AAA144834) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSHMS GQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH. It is sometimes possible for the material contained within the vial of "RAB24, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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