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Possible lysine-specific histone demethylase 1 (Su (var)3-3) Recombinant Protein | Su(var)3-3 recombinant protein

Recombinant Drosophila melanogaster Possible lysine-specific histone demethylase 1 (Su (var)3-3), partial

Gene Names
Su(var)3-3; CG17149; dLsd1; dLSD1; Dmel/HDM; Dmel/LSD1; DmelCG17149; DmelLSD1; Hdm; lsd1; Lsd1; LSD1; SU(VAR)3-3; Su-var(3)3; Suvar(3)3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Possible lysine-specific histone demethylase 1 (Su (var)3-3); Recombinant Drosophila melanogaster Possible lysine-specific histone demethylase 1 (Su (var)3-3); partial; Su(var)3-3 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Length
890
Species
Drosophila melanogaster (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
98,389 Da
NCBI Official Full Name
suppressor of variegation 3-3, isoform A
NCBI Official Synonym Full Names
Suppressor of variegation 3-3
NCBI Official Symbol
Su(var)3-3
NCBI Official Synonym Symbols
CG17149; dLsd1; dLSD1; Dmel/HDM; Dmel/LSD1; DmelCG17149; DmelLSD1; Hdm; lsd1; Lsd1; LSD1; SU(VAR)3-3; Su-var(3)3; Suvar(3)3
NCBI Protein Information
CG17149 gene product from transcript CG17149-RA
UniProt Protein Name
Possible lysine-specific histone demethylase 1
UniProt Gene Name
Su(var)3-3
UniProt Synonym Gene Names
Hdm; LSD1

Uniprot Description

Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for heterochromatic gene silencing. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and tri-methylated 'Lys-4' of histone H3. May also demethylate 'Lys-9' of histone H3, Plays a role in the repression of neuronal genes.

Research Articles on Su(var)3-3

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Product Notes

The Su(var)3-3 su(var)3-3 (Catalog #AAA1447049) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Possible lysine-specific histone demethylase 1 (Su (var)3-3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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