POU domain, class 5, transcription factor 1.1 (pou5f1.1) Recombinant Protein | pou5f1.1 recombinant protein
Recombinant Xenopus laevis POU domain, class 5, transcription factor 1.1 (pou5f1.1)
NCBI and Uniprot Product Information
Uniprot Description
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Activates transcription when directly bound to the octamer DNA sequence, but can form repression complexes with other proteins at the promoter site to inhibit transcription. Binds to the promoter of the vent2-B gene to activate transcription when in the presence of other BMP signaling factors also bound to the promoter. Inhibits the competence of ectodermal cells to respond to BMP during embryogenesis thereby inhibiting epidermal differentiation and promoting neural induction. Antagonizes the activity of nodal/activin signaling by forming a transcriptional repression complex on the gsc and mix2 gene promoters to inhibit their transcription, and thus maintain the undifferentiated state of embryonic cells to prevent them from differentiating prematurely. Acts maternally to inhibit vegt and beta-catenin-activated gene transcription by forming a transcriptional repression complex on the nodal/nr1 and siamois promoters to inhibit their transcription.
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Product Notes
The pou5f1.1 pou5f1.1 (Catalog #AAA1443449) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-449, Full length protein. The amino acid sequence is listed below: MYSQQPFPAF AFNAGLMQDP ANCHFGGYTG LGHPQPFSFA FSTLKSENGE SGVQGMGDCT TPVMPWNSLA SFDHQVQMEN NQQGNPPRAP SPTLSDSRIK VKEEVVHETD SGEESPEPKY PSPPNPSLYY PNAWTGAPFW QVNPTPGNNI NPMPNQTLVK NTSLPGNTTY PTPANQSPNT PVDCVTSSME SSRCSSTNSP NGAINERATT IPNGEMLDGG QSSDNEEEVP SESEMEQFAK DLKHKRVSLG YTQADVGYAL GVLYGKMFSQ TTICRFESLQ LSFKNMCQLK PFLERWVVEA ENNDNLQELI NREQVIAQTR KRKRRTNIEN IVKGTLESYF MKCPKPGAQE MVQIAKELNM DKDVVRVWFC NRRQKGKRQG MPTVEENDGE GYDVAQTMGS PPVGHYALQQ VVTPQGYMAA PQIYASAFHK NDLFPQTVPH GMAMGGHIG. It is sometimes possible for the material contained within the vial of "POU domain, class 5, transcription factor 1.1 (pou5f1.1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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