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Methionine Sulfoxide Reductase B2 Recombinant Protein | MSRB2 recombinant protein

Recombinant Human Methionine Sulfoxide Reductase B2

Gene Names
MSRB2; CBS1; MSRB; PILB; CBS-1; CGI-131
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Methionine Sulfoxide Reductase B2; Recombinant Human Methionine Sulfoxide Reductase B2; MSRB2 Human; Methionine Sulfoxide Reductase B2 Human Recombinant; CBS-1; PILB; Pilin-like Transcription Factor; MSRB; CGI-131; Mmethionine Sulfoxide Reductase B2; Methionine-R-Sulfoxide Reductase B2 Mitochondrial; MGC26104; MsrB2. EC 1.8.4; MSRB2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
The MSRB2 protein solution (1mg/1ml) is formulated in In 20 mM Tris-HCl Buffer (pH 7.5), 1 mM DTT, 0.1 mM PMSF and 10% Glycerol.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MVRGQAGGGG PGTGPGLGEA GSLATCELPL AKSEWQKKLT PEQFYVTREK GTEPPFSGIY LNNKEAGMYH CVCCDSPLFS SEKKYCSGTG WPSFSEAHGT SGSDESHTGI LRRLDTSLGS ARTEVVCKQC EAHLGHVFPD GPGPNGQRFC INSVALKFKP RKH
Sequence Length
182
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.
Related Product Information for MSRB2 recombinant protein
Description: MSRB2 produced in E Coli is a single, non-glycosylated polypeptide chain containing 183 amino acids (21-182a.a.) and having a molecular mass of 19.5kDa.MSRB2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Introduction: MSRB2 is a member of the methionine sulfoxide reductases(MSRs) family which are antioxidant repair enzymes. MSRB2 protein catalyzes the decrease of free and protein-bound methionine sulfoxide to methionine. MSRB2 has a part in protecting against oxidative stress in numerous organs.
Product Categories/Family for MSRB2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,536 Da
NCBI Official Full Name
methionine-R-sulfoxide reductase B2, mitochondrial
NCBI Official Synonym Full Names
methionine sulfoxide reductase B2
NCBI Official Symbol
MSRB2
NCBI Official Synonym Symbols
CBS1; MSRB; PILB; CBS-1; CGI-131
NCBI Protein Information
methionine-R-sulfoxide reductase B2, mitochondrial; pilin-like transcription factor
UniProt Protein Name
Methionine-R-sulfoxide reductase B2, mitochondrial
UniProt Gene Name
MSRB2
UniProt Synonym Gene Names
CBS-1; MSRB; MsrB2
UniProt Entry Name
MSRB2_HUMAN

Uniprot Description

MSRB2: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. Belongs to the MsrB Met sulfoxide reductase family.

Protein type: Transcription factor; Oxidoreductase; EC 1.8.4.-; Mitochondrial

Chromosomal Location of Human Ortholog: 10p12

Cellular Component: mitochondrion

Molecular Function: zinc ion binding; peptide-methionine (R)-S-oxide reductase activity; actin binding; transcription factor activity

Biological Process: protein repair; regulation of transcription, DNA-dependent; actin filament polymerization; response to oxidative stress

Research Articles on MSRB2

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Product Notes

The MSRB2 msrb2 (Catalog #AAA144168) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MVRGQA GGGG PGTGPGLGEA GSLATCELPL AKSEWQKKLT PEQFYVTREK GTEPPFSGIY LNNKEAGMYH CVCCDSPLFS SEKKYCSGTG WPSFSEAHGT SGSDESHTGI LRRLDTSLGS ARTEVVCKQC EAHLGHVFPD GPGPNGQRFC INSVALKFKP RKH. It is sometimes possible for the material contained within the vial of "Methionine Sulfoxide Reductase B2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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