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Nuclease EXOG, mitochondrial (EXOG) Recombinant Protein | EXOG recombinant protein

Recombinant Human Nuclease EXOG, mitochondrial (EXOG)

Gene Names
EXOG; ENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Nuclease EXOG; mitochondrial (EXOG); Recombinant Human Nuclease EXOG; EXOG recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
42-368, Full length protein
Sequence
QGAEGALTGKQPDGSAEKAVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPS
Sequence Length
327
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for EXOG recombinant protein
This gene encodes an endo
exonuclease with 5 -3 exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5 end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,437 Da
NCBI Official Full Name
nuclease EXOG, mitochondrial isoform 2
NCBI Official Synonym Full Names
exo/endonuclease G
NCBI Official Symbol
EXOG
NCBI Official Synonym Symbols
ENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2
NCBI Protein Information
nuclease EXOG, mitochondrial
UniProt Protein Name
Nuclease EXOG, mitochondrial
Protein Family
UniProt Gene Name
EXOG
UniProt Synonym Gene Names
ENDOGL1; ENDOGL2; ENGL; Endo G-like 1

NCBI Description

This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]

Uniprot Description

Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.

Research Articles on EXOG

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Product Notes

The EXOG exog (Catalog #AAA1425927) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 42-368, Full length protein. The amino acid sequence is listed below: QGAEGALTGK QPDGSAEKAV LEQFGFPLTG TEARCYTNHA LSYDQAKRVP RWVLEHISKS KIMGDADRKH CKFKPDPNIP PTFSAFNEDY VGSGWSRGHM APAGNNKFSS KAMAETFYLS NIVPQDFDNN SGYWNRIEMY CRELTERFED VWVVSGPLTL PQTRGDGKKI VSYQVIGEDN VAVPSHLYKV ILARRSSVST EPLALGAFVV PNEAIGFQPQ LTEFQVSLQD LEKLSGLVFF PHLDRTSDIR NICSVDTCKL LDFQEFTLYL STRKIEGARS VLRLEKIMEN LKNAEIEPDD YFMSRYEKKL EELKAKEQSG TQIRKPS. It is sometimes possible for the material contained within the vial of "Nuclease EXOG, mitochondrial (EXOG), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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