Urate Oxidase Active Protein | Uox active protein
Recombinant Urate Oxidase
Gene Names
Uox; Uri; Uri2; UOX-2
Purity
Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Urate Oxidase; Recombinant Urate Oxidase; Uricase; Urate Oxygen; Oxidoreductase; UOX; UO; EC 1.7.3.; Uox active protein
Purity/Purification
Greater than 96.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
Each 1.5mg Uricase contains 5mg sucrose, 25mg glycine, 0.1mg Tween-80, 13.6 mg Na2HPO4*12H2O and 0.33 mg NaH2PO4*2H2O.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
msavkaaryg kdnvrvykvh kdektgvqtv yemtvcvlle geietsytka dnsvivatds ikntiyitak qnpvtppelf gsilgthfie kynhihaahv nivchrwtrm didgkphphs firdseekrn vqvdvvegkg idiksslsgl tvlkstnsqf wgflrdeytt lketwdrils tdvdatwqwk nfsglqevrs hvpkfdatwa tarevtlktf aednsasvqa tmykmaeqil arqqlietve yslpnkhyfe idlswhkglq ntgknaevfa pqsdpnglik ctvgrsslks kl
Sequence Length
303
Source
E. coli
Solubility
We highly recommend reconstituting the lyophilized Uricase in 50mM borate buffer containing 0.001%Triton X-100 and 1.0mM EDTA, pH 8.5 for activity assay.
Biological Activity
The specific activity was found to be 10U/mg.One Unit oxidizes one micromole of uric acid per minute at 25 degree C, at pH 8.5.
Preparation and Storage
Lyophilized Urate Oxidase although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Uricase should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
Related Product Information for Uox active protein
Description: Urate Oxidase Recombinant produced in E Coli is a tetrameric, non-glycosylated polypeptide chain containing 302 amino acids, having a molecular formula of C1523H2383N417O462S7 and a molecular mass of 34,247 Dalton.The cDNA coding for urate-oxidase was cloned from a strain of Aspergillus flavus. The monomer protein has no intra- or inter-disulfide bridges.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,247 Da
NCBI Official Full Name
uricase
NCBI Official Synonym Full Names
urate oxidase
NCBI Official Symbol
Uox
NCBI Official Synonym Symbols
Uri; Uri2; UOX-2
NCBI Protein Information
uricase; urate oxidase 2
UniProt Protein Name
Uricase
UniProt Gene Name
Uox
UniProt Entry Name
URIC_RAT
NCBI Description
catalyzes the hydrolysis of uric acid to allantoin in purine degradation [RGD, Feb 2006]
Uniprot Description
uricase: Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.
Protein type: EC 1.7.3.3; Oxidoreductase; Mitochondrial
Cellular Component: peroxisomal matrix; mitochondrion; peroxisome
Molecular Function: urate oxidase activity
Biological Process: urate catabolic process; purine base catabolic process
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Product Notes
The Uox uox (Catalog #AAA142453) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: msavkaaryg kdnvrvykvh kdektgvqtv yemtvcvlle geietsytka dnsvivatds ikntiyitak qnpvtppelf gsilgthfie kynhihaahv nivchrwtrm didgkphphs firdseekrn vqvdvvegkg idiksslsgl tvlkstnsqf wgflrdeytt lketwdrils tdvdatwqwk nfsglqevrs hvpkfdatwa tarevtlktf aednsasvqa tmykmaeqil arqqlietve yslpnkhyfe idlswhkglq ntgknaevfa pqsdpnglik ctvgrsslks kl. It is sometimes possible for the material contained within the vial of "Urate Oxidase, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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