DNA damage-binding protein 1a (DDB1A) Recombinant Protein | DDB1A recombinant protein

Recombinant Arabidopsis thaliana DNA damage-binding protein 1a (DDB1A) , partial

• Gene Names: DDB1A; C6L9.100; C6L9_100; damaged DNA binding protein 1A
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: DNA damage-binding protein 1a (DDB1A); Recombinant Arabidopsis thaliana DNA damage-binding protein 1a (DDB1A); partial; DDB1A recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1088

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 15235577
• NCBI GeneID: 825890
• NCBI Accession #: NP_192451.1
• NCBI GenBank Nucleotide #: NM_116781.3
• UniProt Accession #: Q9M0V3; Q0WL42; Q8VY31
• Molecular Weight: 121,306 Da
• NCBI Official Full Name: damaged DNA binding protein 1A
• NCBI Official Symbol: DDB1A
• NCBI Official Synonym Symbols: C6L9.100; C6L9_100; damaged DNA binding protein 1A
• NCBI Protein Information: damaged DNA binding protein 1A
• UniProt Protein Name: DNA damage-binding protein 1a
• Protein Family: DNA damage-binding protein
• UniProt Gene Name: DDB1A
• UniProt Synonym Gene Names: DDB1a

NCBI Description

Structurally similar to damaged DNA binding proteins. DDB1a is part of a 350 KDa nuclear localized DET1 protein complex. This complex may physically interact with histone tails and while bound to chromatin- repress transcription of genes involved in photomorphogenesis. DDB1a is shown to be RUB-modified.

Uniprot Description

Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB). Component of the CUL4-RBX1-DDB1-PRL1 E3 ubiquitin-protein ligase complex.