Surfactant Protein D Recombinant Protein | SFTPD recombinant protein
Recombinant Human Surfactant Protein D, Sf9
Gene Names
SFTPD; SP-D; PSP-D; SFTP4; COLEC7
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Surfactant Protein D; Recombinant Human Surfactant Protein D; Sf9; Surfactant Protein D Human Recombinant; Lung Surfactant Protein D; Collectin-7; COLEC7; SFTP4; PSP-D; SP-D; Surfactant-Associated Protein; Pulmonary 4; Surfactant; Pulmonary-Associated Protein D; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactant Apoprotein; PSPD; SFTPD Human; SFTPD recombinant protein
Host
Sf9, Baculovirus cells
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
Sterile filtered colorless solution.
Protein solution (0.25mg/ml) contains 10% glycerol & Phosphate Buffered Saline (pH 7.4).
Protein solution (0.25mg/ml) contains 10% glycerol & Phosphate Buffered Saline (pH 7.4).
Sequence
ADPEMKTYSH RTMPSACTLV MCSSVESGLP GRDGRDGREG PRGEKGDPGL PGAAGQAGMP GQAGPVGPKG DNGSVGEPGP KGDTGPSGPP GPPGVPGPAG REGPLGKQGN IGPQGKPGPK GEAGPKGEVG APGMQGSAGA RGLAGPKGER GVPGERGVPG NTGAAGSAGA GPQGSPGAR GPPGLKGDKG IPGDKGAKGE SGLPDVASLR QQVEALQGQV QHLQAAFSQY KKVELFPNGQ SVGEKIFKTA GFVKPFTEAQ LLCTQAGGQL ASPRSAAENA ALQQLVVAKN EAAFLSMTDS KTEGKFTYPT GESLVYSNWA PGEPNDDGGS EDCVEIFTNG KWNDRACGEK RLVVCEFHHH HHH.
Sequence Length
375
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Related Product Information for SFTPD recombinant protein
Description: SFTPD produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 363 amino acids (22-375 a.a.) and having a molecular mass of 36.5kDa. (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). SFTPD is expressed with a 9 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Introductions: Surfactant pulmonary-associated protein D (SFTPD) belongs to the collectin family of C-type lectins, which is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. SFTPD has humoral molecules of the innate immune system, and is deemed a functional candidate in chronic periodontitis. Moreover, SFTPD is involved in the development of acute and chronic inflammation of the lung. A number of human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. SFTPD contributes to the lungs defense against inhaled microorganisms, organic antigens and toxins. SFTPD interacts with complexes such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. In addition, SFTPD participates in the extracellular reorganization or turnover of pulmonary surfactant. SFTPD binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Introductions: Surfactant pulmonary-associated protein D (SFTPD) belongs to the collectin family of C-type lectins, which is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. SFTPD has humoral molecules of the innate immune system, and is deemed a functional candidate in chronic periodontitis. Moreover, SFTPD is involved in the development of acute and chronic inflammation of the lung. A number of human lung diseases are characterized by decreased levels of bronchoalveolar SFTPD. SFTPD contributes to the lungs defense against inhaled microorganisms, organic antigens and toxins. SFTPD interacts with complexes such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. In addition, SFTPD participates in the extracellular reorganization or turnover of pulmonary surfactant. SFTPD binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Product Categories/Family for SFTPD recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
37,728 Da
NCBI Official Full Name
Pulmonary surfactant-associated protein D
NCBI Official Synonym Full Names
surfactant protein D
NCBI Official Symbol
SFTPD
NCBI Official Synonym Symbols
SP-D; PSP-D; SFTP4; COLEC7
NCBI Protein Information
pulmonary surfactant-associated protein D
UniProt Protein Name
Pulmonary surfactant-associated protein D
Protein Family
UniProt Gene Name
SFTPD
UniProt Synonym Gene Names
COLEC7; PSPD; SFTP4; PSP-D; SP-D
NCBI Description
The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]
Uniprot Description
Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
Research Articles on SFTPD
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Product Notes
The SFTPD sftpd (Catalog #AAA141276) is a Recombinant Protein produced from Sf9, Baculovirus cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ADPEMKTYSH RTMPSACTLV MCSSVESGLP GRDGRDGREG PRGEKGDPGL PGAAGQAGMP GQAGPVGPKG DNGSVGEPGP KGDTGPSGPP GPPGVPGPAG REGPLGKQGN IGPQGKPGPK GEAGPKGEVG APGMQGSAGA RGLAGPKGER GVPGERGVPG NTGAAGSAGA GPQGSPGAR GPPGLKGDKG IPGDKGAKGE SGLPDVASLR QQVEALQGQV QHLQAAFSQY KKVELFPNGQ SVGEKIFKTA GFVKPFTEAQ LLCTQAGGQL ASPRSAAENA ALQQLVVAKN EAAFLSMTDS KTEGKFTYPT GESLVYSNWA PGEPNDDGGS EDCVEIFTNG KWNDRACGEK RLVVCEFHHH HHH. It is sometimes possible for the material contained within the vial of "Surfactant Protein D, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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