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Phenylalanyl-TRNA Synthetase Beta Recombinant Protein | FARSB recombinant protein

Recombinant Human Phenylalanyl-TRNA Synthetase Beta

Gene Names
FARSB; FRSB; PheHB; PheRS; FARSLB; HSPC173
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Phenylalanyl-TRNA Synthetase Beta; Recombinant Human Phenylalanyl-TRNA Synthetase Beta; FARSB Human; Phenylalanyl-TRNA Synthetase Beta Human Recombinant; Phenylalanyl-TRNA Synthetase; Beta Subunit; FARSLB;FRSB; Phenylalanyl-TRNA Synthetase-Like; EC 6.1.1.20; PheRS; Phenylalanine-TRNA Synthetase-Like; Phenylalanine TRNA Ligase 1; Beta; Cytoplasmic; Phenylalanyl-TRNA Synthetase Beta-Subunit; Phenylalanyl-TRNA Synthetase Beta Subunit; Phenylalanine--TRNA Ligase Beta Subunit; Phenylalanyl-TRNA Synthetase Beta Chain; Phenylalanine--TRNA Ligase Beta Chain; Phenylalanine-TRNA Ligase Beta Chain; EC 6.1.1; HSPC173;PheHB;Beta;FARSB; FARSB recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
FARSB protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMPTVSVK RDLLFQALGR TYTDEEFDEL CFEFGLELDE ITSEKEIISK EQGNVKAAGA SDVVLYKIDV PANRYDLLCL EGLVRGLQVF KERIKAPVYK RVMPDGKIQK LIITEETAKI RPFAVAAVLR NIKFTKDRYD SFIELQEKLH QNICRKRALV AIGTHDLDTL SGPFTYTAKR PSDIKFKPLN KTKEYTACEL MNIYKTDNHL KHYLHIIENK PLYPVIYDSN GVVLSMPPII NGDHSRITVN TRNIFIECTG TDFTKAKIVL DIIVTMFSEY CENQFTVEAA EVVFPNGKSH TFPELAYRKE MVRADLINKK VGIRETPENL AKLLTRMYLK SEVIGDGNQI EIEIPPTRAD IIHACDIVED AAIAYGYNNI QMTLPKTYTI ANQFPLNKLT ELLRHDMAAA GFTEALTFAL CSQEDIADKL GVDISATKAV HISNPKTAEF QVARTTLLPG LLKTIAANRK MPLPLKLFEI SDIVIKDSNT DVGAKNYRHL CAVYYNKNPG FEIIHGLLDR IMQLLDVPPG EDKGGYVIKA SEGPAFFPGR CAEIFARGQS VGKLGVLHPD VITKFELTMP CSSLEINVGP FL
Sequence Length
589
Related Product Information for FARSB recombinant protein
Introduction: FARSB, also known as Phenylalanyl-TRNA Synthetase Beta is a member of the phenylalanyl-tRNA synthetase beta subunit family. FARSB is composed tetramer of two alpha and two beta subunits. In the presence of ATP, this tetramer is accountable for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA.

Description: FARSB Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 612 amino acids (1-589 a.a) and having a molecular mass of 68.5kDa.FARSB is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for FARSB recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,861 Da
NCBI Official Full Name
phenylalanine--tRNA ligase beta subunit
NCBI Official Synonym Full Names
phenylalanyl-tRNA synthetase beta subunit
NCBI Official Symbol
FARSB
NCBI Official Synonym Symbols
FRSB; PheHB; PheRS; FARSLB; HSPC173
NCBI Protein Information
phenylalanine--tRNA ligase beta subunit
UniProt Protein Name
Phenylalanine--tRNA ligase beta subunit
UniProt Gene Name
FARSB
UniProt Synonym Gene Names
FARSLB; FRSB; PheRS
UniProt Entry Name
SYFB_HUMAN

Uniprot Description

FARSLB: a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. [provided by RefSeq, Jul 2008]

Protein type: EC 6.1.1.20; Ligase; Translation

Chromosomal Location of Human Ortholog: 2q36.1

Cellular Component: cytoplasm; cytosol; membrane

Molecular Function: phenylalanine-tRNA ligase activity; protein binding

Biological Process: phenylalanyl-tRNA aminoacylation; protein heterotetramerization; translation; tRNA aminoacylation for protein translation

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Product Notes

The FARSB farsb (Catalog #AAA140739) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMPT VSVK RDLLFQALGR TYTDEEFDEL CFEFGLELDE ITSEKEIISK EQGNVKAAGA SDVVLYKIDV PANRYDLLCL EGLVRGLQVF KERIKAPVYK RVMPDGKIQK LIITEETAKI RPFAVAAVLR NIKFTKDRYD SFIELQEKLH QNICRKRALV AIGTHDLDTL SGPFTYTAKR PSDIKFKPLN KTKEYTACEL MNIYKTDNHL KHYLHIIENK PLYPVIYDSN GVVLSMPPII NGDHSRITVN TRNIFIECTG TDFTKAKIVL DIIVTMFSEY CENQFTVEAA EVVFPNGKSH TFPELAYRKE MVRADLINKK VGIRETPENL AKLLTRMYLK SEVIGDGNQI EIEIPPTRAD IIHACDIVED AAIAYGYNNI QMTLPKTYTI ANQFPLNKLT ELLRHDMAAA GFTEALTFAL CSQEDIADKL GVDISATKAV HISNPKTAEF QVARTTLLPG LLKTIAANRK MPLPLKLFEI SDIVIKDSNT DVGAKNYRHL CAVYYNKNPG FEIIHGLLDR IMQLLDVPPG EDKGGYVIKA SEGPAFFPGR CAEIFARGQS VGKLGVLHPD VITKFELTMP CSSLEINVGP FL. It is sometimes possible for the material contained within the vial of "Phenylalanyl-TRNA Synthetase Beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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