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Pyruvate Dehydrogenase Complex Recombinant Protein | PDHX recombinant protein

Recombinant Human Pyruvate Dehydrogenase Complex, Component X

Gene Names
PDHX; E3BP; OPDX; PDX1; proX; DLDBP
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Pyruvate Dehydrogenase Complex; Recombinant Human Pyruvate Dehydrogenase Complex; Component X; PDHX Human; Component X Human Recombinant; DLDBP; E3BP; OPDX; PDX1; proX; Dihydrolipoamide Dehydrogenase-Binding Protein Of Pyruvate Dehydrogenase Complex; Lipoyl-Containing Pyruvate Dehydrogenase Complex Component X; Lipoyl-Containing Component X; E3-Binding Protein Subunit; Pyruvate Dehydrogenase Protein X Component; Mitochondrial; E3-Binding Protein; PDHX recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
PDHX protein solution (0.25mg/ml) containing Phosphate buffer saline (pH 7.4) and 20% glycerol, 1mM DTT.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSGDPIKIL MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK NIRLGSLIGL IVEEGEDWKH VEIPKDVGPP PPVSKPSEPR PSPEPQISIP VKKEHIPGTL RFRLSPAARN ILEKHSLDAS QGTATGPRGI FTKEDALKLV QLKQTGKITE SRPTPAPTAT PTAPSPLQAT AGPSYPRPVI PPVSTPGQPN AVGTFTEIPA SNIRRVIAKR LTESKSTVPH AYATADCDLG AVLKVRQDLV KDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF IDISVAVATD KGLLTPIIKD AAAKGIQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL GMFGIDEFTA VINPPQACIL AVGRFRPVLK LTEDEEGNAK LQQRQLITVT MSSDSRVVDD ELATRFLKSF KANLENPIRL A.
Sequence Length
486
Related Product Information for PDHX recombinant protein
Introduction: Pyruvate Dehydrogenase Complex, Component X, also known as PDHX, encodes the E3 binding protein subunit of the PDH complex which contains 3 catalytic subunits. PDHX tethers E3 dimers to the E2 core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is critical for a functional PDH complex.

Description: PDHX Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 471 amino acids (54-501 a.a) and having a molecular mass of 50.4kDa. PDHX is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for PDHX recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,460 Da
NCBI Official Full Name
pyruvate dehydrogenase protein X component, mitochondrial isoform 2
NCBI Official Synonym Full Names
pyruvate dehydrogenase complex component X
NCBI Official Symbol
PDHX
NCBI Official Synonym Symbols
E3BP; OPDX; PDX1; proX; DLDBP
NCBI Protein Information
pyruvate dehydrogenase protein X component, mitochondrial
UniProt Protein Name
Pyruvate dehydrogenase protein X component, mitochondrial
UniProt Gene Name
PDHX
UniProt Synonym Gene Names
PDX1; E3BP
UniProt Entry Name
ODPX_HUMAN

Uniprot Description

Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.

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Product Notes

The PDHX pdhx (Catalog #AAA140567) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSGDP IKIL MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK NIRLGSLIGL IVEEGEDWKH VEIPKDVGPP PPVSKPSEPR PSPEPQISIP VKKEHIPGTL RFRLSPAARN ILEKHSLDAS QGTATGPRGI FTKEDALKLV QLKQTGKITE SRPTPAPTAT PTAPSPLQAT AGPSYPRPVI PPVSTPGQPN AVGTFTEIPA SNIRRVIAKR LTESKSTVPH AYATADCDLG AVLKVRQDLV KDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF IDISVAVATD KGLLTPIIKD AAAKGIQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL GMFGIDEFTA VINPPQACIL AVGRFRPVLK LTEDEEGNAK LQQRQLITVT MSSDSRVVDD ELATRFLKSF KANLENPIRL A.. It is sometimes possible for the material contained within the vial of "Pyruvate Dehydrogenase Complex, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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