Mouse anti-Human arsA Arsenite Transporter, ATP-Binding, Homolog 1 Monoclonal Antibody | anti-ASNA1 antibody
Mouse Anti Human arsA Arsenite Transporter, ATP-Binding, Homolog 1
Sterile filtered colorless solution.
Stability: 12 months at -20 degree C. 1 month at 4 degree C.
NCBI and Uniprot Product Information
Uniprot Description
ASNA1: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting. May be involved in insulin signaling. Belongs to the arsA ATPase family.
Protein type: EC 3.6.-.-; EC 3.6.3.16; Hydrolase; Nucleolus
Chromosomal Location of Human Ortholog: 19q13.3
Cellular Component: cytoplasm; endoplasmic reticulum membrane; nucleolus; nucleus
Molecular Function: arsenite transmembrane transporter activity; ATPase activity, coupled to movement of substances; protein binding; transporter activity
Biological Process: transport
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Product Notes
The ASNA1 asna1 (Catalog #AAA140504) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human arsA Arsenite Transporter, ATP-Binding, Homolog 1 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's arsA Arsenite Transporter, ATP-Binding, Homolog 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Researchers should empirically determine the suitability of the ASNA1 asna1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "arsA Arsenite Transporter, ATP-Binding, Homolog 1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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