Mouse anti-Human AminoAcylase-1 Monoclonal Antibody | anti-ACY1 antibody

Mouse Anti Human AminoAcylase-1

Cat. Num. AAA140468

• Gene Names: ACY1; ACY-1; ACY1D; HEL-S-5
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Purified from mouse ascitic fluids by protein-A affinity chromatography
• Synonyms: AminoAcylase-1; Monoclonal Antibody; Mouse Anti Human AminoAcylase-1; ACY1 Antibody; Mouse Anti Human; ACY1D; ACYLASE; ACY-1; EC 3.5.1.143; anti-ACY1 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Clone Number: PAT1E2AT
• Purity/Purification: Purified from mouse ascitic fluids by protein-A affinity chromatography
• Form/Format: 1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.; Sterile filtered colorless solution.
• Sequence Length: 408

• Applicable Applications for anti-ACY1 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: ACY1 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity.
• Ig Subclass: Mouse IgG2b heavy chain and k light chain.
• Immunogen: Anti-human ACY1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ACY1 amino acids 1-408 purified from E Coli.
• Preparation and Storage: Storage: For periods up to 1 month store at 4 degree C, for longer periods of time, store at -20 degree C. Prevent freeze thaw cycles.; Stability: 12 months at -20 degree C. 1 month at 4 degree C.

Related Product Information for anti-ACY1 antibody

ACY1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to take part in the catabolism and salvage of acylated amino acids. Defects in ACY1 are the source of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. Epileptic seizures are a frequent feature.

Product Categories/Family for anti-ACY1 antibody

Monoclonal Antibodies; Anti-Human Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 178071
• NCBI GeneID: 95
• Molecular Weight: 42,195 Da
• NCBI Official Full Name: aminoacylase-1
• NCBI Official Synonym Full Names: aminoacylase 1
• NCBI Official Symbol: ACY1
• NCBI Official Synonym Symbols: ACY-1; ACY1D; HEL-S-5
• NCBI Protein Information: aminoacylase-1
• UniProt Protein Name: Aminoacylase-1
• Protein Family: Aminoacylase
• UniProt Gene Name: ACY1
• UniProt Synonym Gene Names: ACY-1
• UniProt Entry Name: ACY1_HUMAN

Uniprot Description

Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).