Rat CD11b Monoclonal Antibody | anti-CD11b antibody
Rat Anti Mouse CD11b FITC
Gene Names
ITGAM; CD11B
Purity
Ion exchange column.
Synonyms
CD11b; Monoclonal Antibody; Rat Anti Mouse CD11b FITC; CD11b FITC Antibody; CD11b FITC; Rat Anti-Mouse; Integrin; alpha M; CR3A; MO1A; CD11B; MAC-1; MAC1A; MGC117044; ITGAM TypeRat Anti Mouse Monoclonal; anti-CD11b antibody
Host
Rat
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
mCD11b
Purity/Purification
Ion exchange column.
Concentration
1mg/ml in PBS (after reconstitution). (varies by lot)
Sequence Length
920
Reconstitution
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen
Purified mouse LN CD4+ T cells.
Antibody Properties
Staining and blocking antibody. For staining, use 10 ul/1,000,000 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator.
Available Conjugates
This antibody is only available conjugated to FITC.
Preparation and Storage
Lyophilized: store at 4 degree C. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Related Product Information for anti-CD11b antibody
Introduction: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Integrin alpha-m/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD-11b is identical with cr-3, the receptor for the ic3b fragment of the third complement component. CD-11b probably recognizes the r-g-d peptide in c3b. Integrin alpha-m/beta-2 is also a receptor for fibrinogen, factor x and icam1. it recognizes p1 and p2 peptides of fibrinogen gamma chain.
Product Categories/Family for anti-CD11b antibody
NCBI and Uniprot Product Information
Research Articles on CD11b
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Product Notes
The CD11b cd11b (Catalog #AAA140037) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CD11b, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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