Vacuolar protein sorting-associated protein 33B (Vps33b) Recombinant Protein | Vps33b recombinant protein
Recombinant Rat Vacuolar protein sorting-associated protein 33B (Vps33b)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Vacuolar protein sorting-associated protein 33B (Vps33b); Recombinant Rat Vacuolar protein sorting-associated protein 33B (Vps33b); Vps33b recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-617, full length protein
Sequence
AFPHRLDAPELPDFSMLKRLARDQLIYLLEQLPGKKDLFIEADLMSPLDRIANVSILKQHEVDKLYKVENKLTLSSNEQLCFLVRPRIKTMRYIANLVNADKLAGRVRKYKIILSPQKFYACEMVLEEEGVYGDVSCDEWAFSLLPLDVDLLSMELPEFFRDYFLEGDQRWINTVAQALHLLSTLYGPFPNCYGIGRCTKMSYDLWRKLEEEEDSETKGRRPEIGHIFLLDRDVDFVTALCSQVVYEGLVDDTFRIKCGSVDFGPEVTSSDKSLKVLLNAEDKVFSEIRNEHFSNVFGFLSQKARNLQAQYDRRRGMDIKQMKNFVSQELKGLKQEHRLLSLHIGACESIMKKKTKQDFQELIKTEHALLEGFNIRESTSYIEEHIDRQVSPIESLRLMCLLSITENGLIPKDYRSLKTQYLQSYGPEHLLTFSNLRRAGLLTEQASGDTLTAVENKVSKLVTDKAAGKITDAFSSLAKRSNFRAISKKLNLIPRVDGEYDLKVPRDMAYVFSGAYVPLSCRIIEQVLDRRSWQGLDEVVRLLNCSDFAFTDMAKEDKASSESLRLILVVFLGGCTFSEISALRFLGREKGYRFIFLTTAVTNSARLMEAMSEVKS
Sequence Length
616
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Vps33b recombinant protein
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes
lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome
lysosome pathway.
lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome
lysosome pathway.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
70,693 Da
NCBI Official Full Name
vacuolar protein sorting-associated protein 33B
NCBI Official Synonym Full Names
VPS33B, late endosome and lysosome associated
NCBI Official Symbol
Vps33b
NCBI Protein Information
vacuolar protein sorting-associated protein 33B
UniProt Protein Name
Vacuolar protein sorting-associated protein 33B
Protein Family
UniProt Gene Name
Vps33b
UniProt Synonym Gene Names
r-vps33b
NCBI Description
role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion [RGD, Feb 2006]
Uniprot Description
May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity. Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes ().
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Product Notes
The Vps33b vps33b (Catalog #AAA1375195) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-617, full length protein. The amino acid sequence is listed below: AFPHRLDAPE LPDFSMLKRL ARDQLIYLLE QLPGKKDLFI EADLMSPLDR IANVSILKQH EVDKLYKVEN KLTLSSNEQL CFLVRPRIKT MRYIANLVNA DKLAGRVRKY KIILSPQKFY ACEMVLEEEG VYGDVSCDEW AFSLLPLDVD LLSMELPEFF RDYFLEGDQR WINTVAQALH LLSTLYGPFP NCYGIGRCTK MSYDLWRKLE EEEDSETKGR RPEIGHIFLL DRDVDFVTAL CSQVVYEGLV DDTFRIKCGS VDFGPEVTSS DKSLKVLLNA EDKVFSEIRN EHFSNVFGFL SQKARNLQAQ YDRRRGMDIK QMKNFVSQEL KGLKQEHRLL SLHIGACESI MKKKTKQDFQ ELIKTEHALL EGFNIRESTS YIEEHIDRQV SPIESLRLMC LLSITENGLI PKDYRSLKTQ YLQSYGPEHL LTFSNLRRAG LLTEQASGDT LTAVENKVSK LVTDKAAGKI TDAFSSLAKR SNFRAISKKL NLIPRVDGEY DLKVPRDMAY VFSGAYVPLS CRIIEQVLDR RSWQGLDEVV RLLNCSDFAF TDMAKEDKAS SESLRLILVV FLGGCTFSEI SALRFLGREK GYRFIFLTTA VTNSARLMEA MSEVKS. It is sometimes possible for the material contained within the vial of "Vacuolar protein sorting-associated protein 33B (Vps33b), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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