N-lysine methyltransferase SMYD2-B (smyd2b) Recombinant Protein | smyd2b recombinant protein
Recombinant Danio rerio N-lysine methyltransferase SMYD2-B (smyd2b)
Gene Names
smyd2b; zgc:136609; si:dkey-121j17.3
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
N-lysine methyltransferase SMYD2-B (smyd2b); Recombinant Danio rerio N-lysine methyltransferase SMYD2-B (smyd2b); smyd2b recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-434, Full length protein
Sequence
MMKAEGIPGIEQFASPGKGRGLRVSRAYGVGELLFSCPAYSYVLSVGERGLICEQCFTRKKGLAKCGKCKKAFYCNANCQKKNWPMHKLECQAMCAFGENWRPSETVRLVARIIARLKAQKERSPSEILLLLGEMEAHLEDMDNEKREMTEAHIAGLHQFYSKHLDFPDHQALLTLFSQVHCNGFTVEDEELSNLGLAIFPDIALLNHSCSPNVIVTYRGINAEVRAVKDISPGQEIYTSYIDLLYPTADRLERLRDMYYFSCDCKECTTKSMDVVKMSVRKRSDEIGEKEIKDMVRYARNSMENFRRAKQDKSPTELLEMCELSIDKMSTVFDDSNVYILHMMYQAMGICLFTEDYEGAVRYGEKVIKPFTVLYPAYSMNVASMFLKLGRLYIALDRKLAGIDAFQKALTIMEVVHGKDHTYVTELKQEMRDF
Sequence Length
434
Species
Zebrafish
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,369 Da
NCBI Official Full Name
N-lysine methyltransferase SMYD2-B isoform 2
NCBI Official Synonym Full Names
SET and MYND domain containing 2b
NCBI Official Symbol
smyd2b
NCBI Official Synonym Symbols
zgc:136609; si:dkey-121j17.3
NCBI Protein Information
N-lysine methyltransferase SMYD2-B
UniProt Protein Name
N-lysine methyltransferase SMYD2-B
Protein Family
UniProt Gene Name
smyd2b
Uniprot Description
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860' ().
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Product Notes
The smyd2b smyd2b (Catalog #AAA1367285) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-434, Full length protein. The amino acid sequence is listed below: MMKAEGIPGI EQFASPGKGR GLRVSRAYGV GELLFSCPAY SYVLSVGERG LICEQCFTRK KGLAKCGKCK KAFYCNANCQ KKNWPMHKLE CQAMCAFGEN WRPSETVRLV ARIIARLKAQ KERSPSEILL LLGEMEAHLE DMDNEKREMT EAHIAGLHQF YSKHLDFPDH QALLTLFSQV HCNGFTVEDE ELSNLGLAIF PDIALLNHSC SPNVIVTYRG INAEVRAVKD ISPGQEIYTS YIDLLYPTAD RLERLRDMYY FSCDCKECTT KSMDVVKMSV RKRSDEIGEK EIKDMVRYAR NSMENFRRAK QDKSPTELLE MCELSIDKMS TVFDDSNVYI LHMMYQAMGI CLFTEDYEGA VRYGEKVIKP FTVLYPAYSM NVASMFLKLG RLYIALDRKL AGIDAFQKAL TIMEVVHGKD HTYVTELKQE MRDF. It is sometimes possible for the material contained within the vial of "N-lysine methyltransferase SMYD2-B (smyd2b), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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