Nuclear receptor coactivator 6 (Ncoa6) Recombinant Protein | Ncoa6 recombinant protein
Recombinant Rat Nuclear receptor coactivator 6 (Ncoa6)
Gene Names
Ncoa6; NRC; Aib3; PRIP; Trbp; RAP250
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Nuclear receptor coactivator 6 (Ncoa6); Recombinant Rat Nuclear receptor coactivator 6 (Ncoa6); Ncoa6 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-418, full length protein
Sequence
EQIMTNQMQGNKAQFNSQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVSNSPSQVMGIQGQVLRPPGPSPHMAQQHTDPATTANNDVNLSQMMPDVSMQQTSMVPPHVQSMQGNSASGSHFSGHGVSFNAPFGGAPNGTQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKQKKKKPPRKKKNCHQDLNTPDSRPAGLEEVDQQSLPGEQGINLDNTGPKLPDFSNRPPGYPTQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQPQPQPPPPSQPQSQQQQQQQQQQQQQQMMMMLMMQQDPKSIRLPVSQNVHPPRGPLNPDSQRVPMQQSGNVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNSSS
Sequence Length
418
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Ncoa6 recombinant protein
This protein is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
45,574 Da
NCBI Official Full Name
Nuclear receptor coactivator 6
NCBI Official Synonym Full Names
nuclear receptor coactivator 6
NCBI Official Symbol
Ncoa6
NCBI Official Synonym Symbols
NRC; Aib3; PRIP; Trbp; RAP250
NCBI Protein Information
nuclear receptor coactivator 6
UniProt Protein Name
Nuclear receptor coactivator 6
Protein Family
UniProt Gene Name
Ncoa6
UniProt Synonym Gene Names
Aib3; Rap250; Trbp; ASC-2; NRC; PPAR-interacting protein; PRIP
NCBI Description
interacts with nuclear hormone receptors to activate gene transcription [RGD, Feb 2006]
Uniprot Description
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivate expression in an agonist- and AF2-dependent manner. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway ().
Research Articles on Ncoa6
Similar Products
Product Notes
The Ncoa6 ncoa6 (Catalog #AAA1361030) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-418, full length protein. The amino acid sequence is listed below: EQIMTNQMQG NKAQFNSQNQ SNVMPGPAQI MRGPTPNMQG NMVQFTGQMS GQMLPQQGPV SNSPSQVMGI QGQVLRPPGP SPHMAQQHTD PATTANNDVN LSQMMPDVSM QQTSMVPPHV QSMQGNSASG SHFSGHGVSF NAPFGGAPNG TQMSCGQNPG FPVNKDVTLT SPLLVNLLQS DISAGHFGVN NKQNNTNANK QKKKKPPRKK KNCHQDLNTP DSRPAGLEEV DQQSLPGEQG INLDNTGPKL PDFSNRPPGY PTQPVEQRPL QQMPPQLMQH VAPPPQPPQQ QPQPQLPQQQ PQPQPPPPSQ PQSQQQQQQQ QQQQQQQMMM MLMMQQDPKS IRLPVSQNVH PPRGPLNPDS QRVPMQQSGN VPVMVSLQGP ASVPPSPDKQ RMPMPVNTPL GSNSRKMVYQ ESPQNSSS. It is sometimes possible for the material contained within the vial of "Nuclear receptor coactivator 6 (Ncoa6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
