Phosphothreonine lyase ospF (ospF) Recombinant Protein | ospF recombinant protein
Recombinant Shigella boydii Phosphothreonine lyase ospF (ospF)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Phosphothreonine lyase ospF (ospF); Recombinant Shigella boydii Phosphothreonine lyase ospF (ospF); ospF recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-170, Full length protein
Sequence
PQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPTYSDICQFFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAP
Sequence Length
170
Species
Shigella boydii
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
19,585 Da
NCBI Official Full Name
Phosphothreonine lyase OspF
UniProt Protein Name
Phosphothreonine lyase OspF
Protein Family
UniProt Gene Name
ospF
Uniprot Description
Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3. This epigenetic modification results in inhibition of the transcription of a specific subset of proinflammatory genes, and ultimately to a reduced immune response against the invading pathogen. The diminished immune response enhances the bacterium's ability to disseminate and multiply within the host ().
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Product Notes
The ospF ospf (Catalog #AAA1345537) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-170, Full length protein. The amino acid sequence is listed below: PQMLSANERL KNNFNILYNQ IRQYPAYYFK VASNVPTYSD ICQFFSVMYQ GFQIVNHSGD VFIHACRENP QSKGDFVGDK FHISIAREQV PLAFQILSGL LFSEDSPIDK WKITDMNRVS QQSRVGIGAQ FTLYVKSDQE CSQYSALLLH KIRQFIMCLE SNLLRSKIAP. It is sometimes possible for the material contained within the vial of "Phosphothreonine lyase ospF (ospF), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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