Probable histone-lysine N-methyltransferase set-2 (set-2) Recombinant Protein | set-2 recombinant protein
Recombinant Caenorhabditis elegans Probable histone-lysine N-methyltransferase set-2 (set-2), partial
NCBI and Uniprot Product Information
Uniprot Description
Histone methyltransferase that specifically di- and trimethylates 'Lys-4' of histone H3 at all developmental stages and in adult germ cells (PubMed:21527717, PubMed:20555324). H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (PubMed:21527717). Implicated in the epigenetic inheritance of lifespan over several generations (PubMed:22012258). Acts in the germline to limit the longevity of the soma, probably by regulating a lipid metabolism pathway that signals from the germline to the intestine, thereby preventing accumulation of mono-unsaturated fatty acids (PubMed:20555324, PubMed:28379943). Methylation in the germline is required for germline development and fertility, possibly by ensuring genome stability (PubMed:21527717, PubMed:12242227). May act redundantly with mes-3 and mes-4 proteins in the development of a fertile germline (PubMed:11729150). Required for RNAi (PubMed:17967446). Functions as an antagonist of hpl-1 and hpl-2 activity in growth and somatic gonad development (PubMed:17967446). Cooperates with jmjd-3.1 and egl-27 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development (PubMed:25124442).
Research Articles on set-2
Similar Products
Product Notes
The set-2 set-2 (Catalog #AAA1334035) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Probable histone-lysine N-methyltransferase set-2 (set-2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
