Lysophosphatidylcholine acyltransferase 2 (LPCAT2) Recombinant Protein | LPCAT2 recombinant protein

Recombinant Human Lysophosphatidylcholine acyltransferase 2 (LPCAT2), partial

Cat. Num. AAA1315900

• Gene Names: LPCAT2; AYTL1; AGPAT11; LysoPAFAT
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Lysophosphatidylcholine acyltransferase 2 (LPCAT2); Recombinant Human Lysophosphatidylcholine acyltransferase 2 (LPCAT2); partial; LPCAT2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-57
• Sequence: MSRCAQAAEV AATVPGAGVG NVGLRPPMVP RQASFFPPPV PNPFVQQTQI GSARRVQ
• Sequence Length: 57

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for LPCAT2 recombinant protein

This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi.

NCBI and Uniprot Product Information

• NCBI GI #: 47086907
• NCBI GeneID: 54947
• NCBI Accession #: NP_060309.2
• NCBI GenBank Nucleotide #: NM_017839.4
• UniProt Accession #: Q7L5N7; Q6MZJ6; Q9NX23; A3KBM1
• Molecular Weight: 30,895 Da
• NCBI Official Full Name: lysophosphatidylcholine acyltransferase 2
• NCBI Official Synonym Full Names: lysophosphatidylcholine acyltransferase 2
• NCBI Official Symbol: LPCAT2
• NCBI Official Synonym Symbols: AYTL1; AGPAT11; LysoPAFAT
• NCBI Protein Information: lysophosphatidylcholine acyltransferase 2
• UniProt Protein Name: Lysophosphatidylcholine acyltransferase 2
• Protein Family: Lysophosphatidylcholine acyltransferase
• UniProt Gene Name: LPCAT2
• UniProt Synonym Gene Names: AGPAT11; AYTL1; LPC acyltransferase 2; LPCAT-2; LysoPC acyltransferase 2; 1-AGP acyltransferase 11; 1-AGPAT 11; Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT; LPAAT-alpha

NCBI Description

This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009]

Uniprot Description

Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases. Also catalyzes the conversion of 1-acyl-sn-glycero-3-phosphocholine to 1,2-diacyl-sn-glycero-3-phosphocholine.