Single Ig IL-1-related receptor (Sigirr) Recombinant Protein | Sigirr recombinant protein
Recombinant Rat Single Ig IL-1-related receptor (Sigirr), partial
Gene Names
Sigirr; RGD1306732
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Single Ig IL-1-related receptor (Sigirr); Recombinant Rat Single Ig IL-1-related receptor (Sigirr); partial; Sigirr recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-118
Sequence
MAGVCDRVPN FLSPSEDQAL GPALGSAVAL NCTAWVFSRP QCPQPSVQWL KDGLALGNGS HFSLHQDFWV SDNFSEIVSS VLVFNLTKAE DYGTFTCSAW NVSSHSFTLW RAGPAGHV
Sequence Length
118
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,171 Da
NCBI Official Full Name
single Ig IL-1-related receptor
NCBI Official Synonym Full Names
single Ig and TIR domain containing
NCBI Official Symbol
Sigirr
NCBI Official Synonym Symbols
RGD1306732
NCBI Protein Information
single Ig IL-1-related receptor
UniProt Protein Name
Single Ig IL-1-related receptor
Protein Family
UniProt Gene Name
Sigirr
UniProt Synonym Gene Names
TIR8
Uniprot Description
Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP ().
Research Articles on Sigirr
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Product Notes
The Sigirr sigirr (Catalog #AAA1305451) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-118. The amino acid sequence is listed below: MAGVCDRVPN FLSPSEDQAL GPALGSAVAL NCTAWVFSRP QCPQPSVQWL KDGLALGNGS HFSLHQDFWV SDNFSEIVSS VLVFNLTKAE DYGTFTCSAW NVSSHSFTLW RAGPAGHV. It is sometimes possible for the material contained within the vial of "Single Ig IL-1-related receptor (Sigirr), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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