Forkhead box protein E3 (FOXE3) Recombinant Protein | FOXE3 recombinant protein

Recombinant Human Forkhead box protein E3 (FOXE3)

Cat. Num. AAA1305231

• Gene Names: FOXE3; AAT11; ASGD2; FKHL12; FREAC8; CTRCT34
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Forkhead box protein E3 (FOXE3); Recombinant Human Forkhead box protein E3 (FOXE3); FOXE3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-319, Full length protein
• Sequence: MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPYAPYAPAPGPALLVPPPSAGPGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPDRLVLPATRPGPGPLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL
• Sequence Length: 319

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for FOXE3 recombinant protein

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia.

NCBI and Uniprot Product Information

• NCBI GI #: 11386197
• NCBI GeneID: 2301
• NCBI Accession #: NP_036318.1
• NCBI GenBank Nucleotide #: NM_012186.2
• UniProt Accession #: Q13461; Q5SVY9; Q9NQV9
• Molecular Weight: 33,234 Da
• NCBI Official Full Name: forkhead box protein E3
• NCBI Official Synonym Full Names: forkhead box E3
• NCBI Official Symbol: FOXE3
• NCBI Official Synonym Symbols: AAT11; ASGD2; FKHL12; FREAC8; CTRCT34
• NCBI Protein Information: forkhead box protein E3
• UniProt Protein Name: Forkhead box protein E3
• Protein Family: Forkhead box protein
• UniProt Gene Name: FOXE3
• UniProt Synonym Gene Names: FKHL12; FREAC8; FREAC-8

NCBI Description

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia. [provided by RefSeq, Dec 2009]

Uniprot Description

Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:22527307, PubMed:25504734). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PubMed:27218149).