F-box only protein 7 (Fbxo7) Recombinant Protein | Fbxo7 recombinant protein
Recombinant Mouse F-box only protein 7 (Fbxo7)
Gene Names
Fbxo7; C85118; AI117679; AW260462; 2410015K21Rik; A230052G17Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
F-box only protein 7 (Fbxo7); Recombinant Mouse F-box only protein 7 (Fbxo7); Fbxo7 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-523, Full length protein
Sequence
MKLRVRLQKRTQPLEVPESEPTLGQLRAHLSQVLLPTLGFSSDTRFAITLNNKDALTGDEETLASYGIVSGDLICLVLEDDMPAPNLPSSTDTEHSSLQDNDQPSLAATPSQTNIPDEQGTDSSQGQATPFDAWTDDSMEGPSQNVEAESIQDAMSMEEVSGFHPLEPMLCNETEDGQVPHSLETLYQSAGCSNISDALIVLVHLLMLESGYIPQGTETKAVTMPEKWKSSGVYKLQYTHPLCEGGFAVLTCVPLGNLIIINATIKVNGGIKNVKSVQLQPGSYVAAGVEPGESAAKVYKDLKKLSRLFKDQLVYPLLAFTRQVLNLPDVFGLVVLPLELKLRIFRLLDVHSVLALSAVCHDLLIASNDPLLWRCLYLRDFRDGTVRGPDTDWKELYRKKHIQRKEAQRMRHAMFLPSAHPIPFCPIPVYPRAYLPTSLLPPGIIGGEYDERPILPSVGDPVTSLIPRPGELPGQFRPLRPRFDPVDPLPGPHSLLPGRAIPNNRFPFRPGRGRSADSRLPFL
Sequence Length
523
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Fbxo7 recombinant protein
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. This protein belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,649 Da
NCBI Official Full Name
F-box only protein 7 isoform 3
NCBI Official Synonym Full Names
F-box protein 7
NCBI Official Symbol
Fbxo7
NCBI Official Synonym Symbols
C85118; AI117679; AW260462; 2410015K21Rik; A230052G17Rik
NCBI Protein Information
F-box only protein 7
UniProt Protein Name
F-box only protein 7
Protein Family
UniProt Gene Name
Fbxo7
Uniprot Description
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PRKN to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination ().
Research Articles on Fbxo7
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Product Notes
The Fbxo7 fbxo7 (Catalog #AAA1287002) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-523, Full length protein. The amino acid sequence is listed below: MKLRVRLQKR TQPLEVPESE PTLGQLRAHL SQVLLPTLGF SSDTRFAITL NNKDALTGDE ETLASYGIVS GDLICLVLED DMPAPNLPSS TDTEHSSLQD NDQPSLAATP SQTNIPDEQG TDSSQGQATP FDAWTDDSME GPSQNVEAES IQDAMSMEEV SGFHPLEPML CNETEDGQVP HSLETLYQSA GCSNISDALI VLVHLLMLES GYIPQGTETK AVTMPEKWKS SGVYKLQYTH PLCEGGFAVL TCVPLGNLII INATIKVNGG IKNVKSVQLQ PGSYVAAGVE PGESAAKVYK DLKKLSRLFK DQLVYPLLAF TRQVLNLPDV FGLVVLPLEL KLRIFRLLDV HSVLALSAVC HDLLIASNDP LLWRCLYLRD FRDGTVRGPD TDWKELYRKK HIQRKEAQRM RHAMFLPSAH PIPFCPIPVY PRAYLPTSLL PPGIIGGEYD ERPILPSVGD PVTSLIPRPG ELPGQFRPLR PRFDPVDPLP GPHSLLPGRA IPNNRFPFRP GRGRSADSRL PFL. It is sometimes possible for the material contained within the vial of "F-box only protein 7 (Fbxo7), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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