Peptide-N (4)-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNG1) Recombinant Protein | PNG1 recombinant protein
Recombinant Debaryomyces hansenii Peptide-N (4)-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNG1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Peptide-N (4)-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNG1); Recombinant Debaryomyces hansenii Peptide-N (4)-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNG1); Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; PNGase; EC=3.5.1.52; Peptide:N-glycanase 1; PNG1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-375aa; full length protein
Sequence
MSSQGNKYEY GELADKLILA YSKRRLFKAI GTKRDRQQQF SRLDNKDKRF ISKLIDVSNSNEKHKIPSEL DIALDCIDLA KIYEGVDKRE YERESKAKDP NLIYEDFIVL ELLHYFKHDFFKWVNKPECS RCKQSSNNIV PTGNSGPPSI NPSEISIIEN YKCTKCNIAV SFPRYNNPIKLLETKSGRCG EWVNCFIFIL RALLGSQSQI RYVWNHEDHV WCEYYSLGLK RWIHLDPCEGVFDEPNLYCE NWGKKMSWCF AFGETYIMDV SDKYITKSDK QINKLESVSS LKNIKEFIDTLNDDKLVRYY SNMALTASDE NRNLMRLYQE VILIHNSEKF NKENKIEVSR THNIPTGRQTGDAEWTKSRG EDGNE
Sequence Length
375
Species
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,898 Da
NCBI Official Full Name
DEHA2E21384p
NCBI Official Symbol
DEHA2E21384g
NCBI Protein Information
DEHA2E21384p
UniProt Protein Name
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
Protein Family
UniProt Gene Name
PNG1
UniProt Synonym Gene Names
PNGase
UniProt Entry Name
PNG1_DEBHA
Uniprot Description
Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins ().
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Product Notes
The PNG1 png1 (Catalog #AAA1283304) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-375aa; full length protein. The amino acid sequence is listed below: MSSQGNKYEY GELADKLILA YSKRRLFKAI GTKRDRQQQF SRLDNKDKRF ISKLIDVSNS NEKHKIPSEL DIALDCIDLA KIYEGVDKRE YERESKAKDP NLIYEDFIVL ELLHYFKHDF FKWVNKPECS RCKQSSNNIV PTGNSGPPSI NPSEISIIEN YKCTKCNIAV SFPRYNNPIK LLETKSGRCG EWVNCFIFIL RALLGSQSQI RYVWNHEDHV WCEYYSLGLK RWIHLDPCEG VFDEPNLYCE NWGKKMSWCF AFGETYIMDV SDKYITKSDK QINKLESVSS LKNIKEFIDT LNDDKLVRYY SNMALTASDE NRNLMRLYQE VILIHNSEKF NKENKIEVSR THNIPTGRQT GDAEWTKSRG EDGNE. It is sometimes possible for the material contained within the vial of "Peptide-N (4)-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNG1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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