TUBB1 cdna clone
TUBB1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release. A mutations in this gene is associated with autosomal dominant macrothrombocytopenia. Two pseudogenes of this gene are found on chromosome Y.[provided by RefSeq, Jul 2010]
Uniprot Description
TUBB1: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Dimer of alpha and beta chains. Interacts with RANBP10. Hematopoietic cell-specific. Major isotype in leukocytes, where it represents 50% of all beta-tubulins. Belongs to the tubulin family.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 20q13.32
Cellular Component: cytoplasm
Disease: Macrothrombocytopenia, Autosomal Dominant, Tubb1-related
Research Articles on TUBB1
Similar Products
Product Notes
The TUBB1 tubb1 (Catalog #AAA1277205) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcgtgaaa ttgtccatat tcagattggc cagtgtggca accagatcgg agccaagttc tgggagatga ttggtgagga acacgggatc gacttggctg ggagcgaccg cggggcctcg gccttgcagc tggagagaat cagcgtgtac tacaacgaag cctacggtag gaaatatgtg ccccgagcag tcttggtgga cctagaacct gggacgatgg acagcattcg atctagcaaa ttaggagctc tctttcaacc cgacagtttt gtccatggta actctggggc tggcaacaac tgggccaaag gccactacac ggagggagcc gagctgatcg agaatgtcct agaggtggtg aggcacgaga gtgagagctg tgactgcctg cagggcttcc agatcgtcca ctccctgggc gggggcacag gctccgggat gggcactctg ctcatgaaca agattagaga ggagtacccg gaccggatca tgaattcctt cagcgtcatg ccttctccca aggtgtcgga cacggtggtg gagccctaca acgcggttct gtctatccac cagctgattg agaatgcaga tgcctgtttc tgcattgaca atgaggccct ctatgacatc tgcttccgta ccctgaagct gacgacaccc acctatgggg atctcaacca cctagtgtcc ttgaccatga gcggcataac cacctccctc cggttcccgg gtcagctcaa cgcagacctg cgcaagctgg cggtgaacat ggtccccttc ccccgcctgc acttctttat gcccggcttt gccccactca cggcccaggg cagccagcag taccgagccc tctccgtggc cgagctcacc cagcagatgt tcgatgcccg caataccatg gctgcctgtg acctccgccg tggccgctac ctcacagtgg cctgcatttt ccggggcaag atgtccacca aggaagtgga ccagcaactg ctctccgtgc agaccaggaa cagcagctgc tttgtggagt ggattcccaa caacgtcaag gtggctgtct gcgacatccc gccccggggg ctgagcatgg ccgccacctt cattggcaac aacacggcca tccaagagat ctttaatagg gtctctgagc atttctcagc catgttcaaa aggaaagctt ttgtgcactg gtacaccagc gaagggatgg acataaacga atttggggaa gctgaaaata acatccatga tttggtatcc gagtaccaac aatttcaaga tgccaaagca gttctagagg aagatgaaga ggtcacggag gaggcagaaa tggagccaga agataaggga cattaa. It is sometimes possible for the material contained within the vial of "TUBB1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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