BCL7A cdna clone
BCL7A cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Bcl-7A: Chromosomal aberrations involving BCL7A may be a cause of B-cell non-Hodgkin lymphoma. Three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) with MYC and with immunoglobulin gene regions. Belongs to the BCL7 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Actin-binding
Chromosomal Location of Human Ortholog: 12q24.13
Molecular Function: protein binding
Research Articles on BCL7A
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Product Notes
The BCL7A bcl7a (Catalog #AAA1277065) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtcgggca ggtcggttcg agccgagacg aggagccggg ccaaagatga tatcaagagg gtcatggcgg cgatcgagaa agtgcgcaaa tgggagaaga aatgggtgac cgttggtgac acatccctac gaatctacaa atgggtccct gtgacggagc ccaaggttga tgacaaaaac aagaataaga aaaaaggcaa ggacgagaag tgtggctcag aggtgaccac tccggagaac agttcctccc cagggatgat ggacatgcat gacgataaca gcaaccagag ctccatcgca gatgcctccc ccatcaaaca ggagaacagc agcaactcca gccccgctcc agagcccaac tcggctgtgc ccagcgacgg caccgaggcc aaggtggatg aggcccaggc tgatgggaag gagcacccag gagctgaaga tgcttctgat gagcagaatt cacagtcctc gatggaacat tcgatgaaca gctcagagaa agtagatcgg cagccgtctg gagactcggg tctggccgca gagacgtctg caatctctca ggtacctcgc tcgaggtctc agaggggcag ccagatcggc cgggagccca ttgggttgtc gggggatctg gaaggagtgc caccctctaa aaagatgaaa ctggaggcct ctcaacaaaa ctccgaagag atgtag. It is sometimes possible for the material contained within the vial of "BCL7A, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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