SMAD9 cdna clone
SMAD9 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Uniprot Description
SMAD9: transcription factor phosphorylated and activated by bone morphogenetic protein receptor kinases. Phosphorylated Smads dimerize with collaborating Smad4 and are translocated into the nucleus, where they regulate transcription of target genes. Participates in a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation and apoptosis. Two alternatively spliced products have been described.
Protein type: Transcription, coactivator/corepressor; DNA-binding
Chromosomal Location of Human Ortholog: 13q12-q14
Cellular Component: cytoplasm; cytosol; intracellular; nucleoplasm; nucleus
Molecular Function: protein binding; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
Biological Process: BMP signaling pathway
Disease: Pulmonary Hypertension, Primary, 2
Research Articles on SMAD9
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Product Notes
The SMAD9 smad9 (Catalog #AAA1276345) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcactcca ccacccccat cagctccctc ttctccttca ccagccccgc agtgaagaga ctgctaggct ggaagcaagg agatgaagag gaaaagtggg cagagaaggc agtggactct ctagtgaaga agttaaagaa gaagaaggga gccatggacg agctggagag ggctctcagc tgcccggggc agcccagcaa atgcgtcacg attccccgct ccctggacgg gcggctgcag gtgtcccacc gcaagggcct gccccatgtg atttactgtc gcgtgtggcg ctggccggat ctgcagtccc accacgagct gaagccgctg gagtgctgtg agttcccatt tggctccaag cagaaagaag tgtgcattaa cccttaccac taccgccggg tggagactcc agtactgcct cctgtgctcg tgccaagaca cagtgaatat aacccccagc tcagcctcct ggccaagttc cgcagcgcct ccctgcacag tgagccactc atgccacaca acgccaccta tcctgactct ttccagcagc ctccgtgctc tgcactccct ccctcaccca gccacgcgtt ctcccagtcc ccgtgcacgg ccagctaccc tcactcccca ggaagtcctt ctgagccaga gagtccctat caacactcag actttcgacc agtttgttac gaggagcccc agcactggtg ctcggtcgcc tactatgaac tgaacaaccg agttggggag acattccagg cttcctcccg aagtgtgctc atagatgggt tcaccgaccc ttcaaataac aggaacagat tctgtcttgg acttctttct aatgtaaaca gaaactcaac gatagaaaat accaggagac atataggaaa gggtgtgcac ttgtactacg tcgggggaga ggtgtatgcc gagtgcgtga gtgacagcag catctttgtg cagagccgga actgcaacta tcaacacggc ttccacccag ctaccgtctg caagatcccc agcggctgca gcctcaaggt cttcaacaac cagctcttcg ctcagctcct ggcccagtca gttcaccacg gctttgaagt cgtgtatgaa ctgaccaaga tgtgtactat ccggatgagt tttgttaagg gttggggtgc tgagtatcat cgccaggatg tcaccagcac cccctgctgg attgagattc atcttcatgg gccactgcag tggctggaca aagttctgac tcagatgggc tctccacata accccatttc ttcagtgtct taa. It is sometimes possible for the material contained within the vial of "SMAD9, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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