UBA2 cdna clone
UBA2 cDNA Clone
Gene Names
UBA2; ARX; SAE2; HRIHFB2115
Synonyms
UBA2; UBA2 cDNA Clone; UBA2 cdna clone
Sequence
atggcactgtcgcgggggctgccccgggagctggctgaggcggtggccgggggccgggtgctggtggtgggggcgggcggcatcggctgcgagctcctcaagaatctcgtgctcaccggtttctcccacatcgacctgattgatctggatactattgatgtaagcaacctcaacagacagtttttgtttcaaaagaaacatgttggaagatcaaaggcacaggttgccaaggaaagtgtactgcagttttacccgaaagctaatatcgttgcctaccatgacagcatcatgaaccctgactataatgtggaatttttccgacagtttatactggttatgaatgctttagataacagagctgcccgaaaccatgttaatagaatgtgcctggcagctgatgttcctcttattgaaagtggaacagctgggtatcttggacaagtaactactatcaaaaagggtgtgaccgagtgttatgagtgtcatcctaagccgacccagagaacctttcctggctgtacaattcgtaacacaccttcagaacctatacattgcatcgtttgggcaaagtacttgttcaaccagttgtttggggaagaagatgctgatcaagaagtatctcctgacagagctgaccctgaagctgcctgggaaccaacggaagccgaagccagagctagagcatctaatgaagatggtgacattaaacgtatttctactaaggaatgggctaaatcaactggatatgatccagttaaactttttaccaagctttttaaagatgacatcaggtatctgttgacaatggacaaactatggcggaaaaggaaacctccagttccgttggactgggctgaagtacaaagtcaaggagaagaaacgaatgcatcagatcaacagaatgaaccccagttaggcctgaaagaccagcaggttctagatgtaaagagctatgcacgtcttttttcaaagagcatcgagactttgagagttcatttagcagaaaagggggatggagctgagctcatatgggataaggatgacccatctgcaatggattttgtcacctctgctgcaaacctcaggatgcatattttcagtatgaatatgaagagtagatttgatatcaaatcaatggcagggaacattattcctgctattgctactactaatgcagtaattgctgggttgatagtattggaaggattgaagattttatcaggaaaaatagaccagtgcagaacaatttttttgaataaacaaccaaacccaagaaagaagcttcttgtgccttgtgcactggatcctcccaaccccaattgttatgtatgtgccagcaagccagaggtgactgtgcggctgaatgtccataaagtgactgttctcaccttacaagacaagatagtgaaagaaaaatttgctatggtagcaccagatgtccaaattgaagatgggaaaggaacaatcctaatatcttccgaagagggagagacggaagctaataatcacaagaagttgtcagaatttggaattagaaatggcagccggcttcaagcagatgacttcctccaggactatactttattgatcaacatccttcatagtgaagacctaggaaaggacgttgaatttgaagttgttggtgatgccccggaaaaagtggggcccaaacaagctgaagatgctgccaaaagcataaccaatggcagtgatgatggagctcagccctccacctccacagctcaagagcaagatgacgttctcatagttgattcggatgaagaagattcttcaaataatgccgacgtcagtgaagaagagagaagccgcaagaggaaattagatgagaaagagaatctcagtgcaaagaggtcacgtatagaacagaaggaagagcttgatgatgtcatagcattagattga
Sequence Length
1923
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
60,839 Da
NCBI Official Full Name
Homo sapiens ubiquitin-like modifier activating enzyme 2, mRNA
NCBI Official Synonym Full Names
ubiquitin like modifier activating enzyme 2
NCBI Official Symbol
UBA2
NCBI Official Synonym Symbols
ARX; SAE2; HRIHFB2115
NCBI Protein Information
SUMO-activating enzyme subunit 2
UniProt Protein Name
SUMO-activating enzyme subunit 2
Protein Family
UniProt Gene Name
UBA2
UniProt Synonym Gene Names
SAE2; UBLE1B
UniProt Entry Name
SAE2_HUMAN
NCBI Description
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
Uniprot Description
SAE2: a protein of the ubiquitin-activating E1 family. Acts as a UBL1 E1 ligase. Mediates ATP-dependent activation of UBL1 and formation of a thiolester with a conserved cysteine residue on SAE2.
Protein type: Ubiquitin conjugating system; Ligase; EC 6.3.2.-; EC 6.3.2.19; Ubiquitin ligase; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19q12
Cellular Component: cytosol; nucleoplasm
Molecular Function: enzyme activator activity; protein binding; protein heterodimerization activity; SUMO activating enzyme activity
Biological Process: protein sumoylation
Research Articles on UBA2
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Product Notes
The UBA2 uba2 (Catalog #AAA1275212) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcactgt cgcgggggct gccccgggag ctggctgagg cggtggccgg gggccgggtg ctggtggtgg gggcgggcgg catcggctgc gagctcctca agaatctcgt gctcaccggt ttctcccaca tcgacctgat tgatctggat actattgatg taagcaacct caacagacag tttttgtttc aaaagaaaca tgttggaaga tcaaaggcac aggttgccaa ggaaagtgta ctgcagtttt acccgaaagc taatatcgtt gcctaccatg acagcatcat gaaccctgac tataatgtgg aatttttccg acagtttata ctggttatga atgctttaga taacagagct gcccgaaacc atgttaatag aatgtgcctg gcagctgatg ttcctcttat tgaaagtgga acagctgggt atcttggaca agtaactact atcaaaaagg gtgtgaccga gtgttatgag tgtcatccta agccgaccca gagaaccttt cctggctgta caattcgtaa cacaccttca gaacctatac attgcatcgt ttgggcaaag tacttgttca accagttgtt tggggaagaa gatgctgatc aagaagtatc tcctgacaga gctgaccctg aagctgcctg ggaaccaacg gaagccgaag ccagagctag agcatctaat gaagatggtg acattaaacg tatttctact aaggaatggg ctaaatcaac tggatatgat ccagttaaac tttttaccaa gctttttaaa gatgacatca ggtatctgtt gacaatggac aaactatggc ggaaaaggaa acctccagtt ccgttggact gggctgaagt acaaagtcaa ggagaagaaa cgaatgcatc agatcaacag aatgaacccc agttaggcct gaaagaccag caggttctag atgtaaagag ctatgcacgt cttttttcaa agagcatcga gactttgaga gttcatttag cagaaaaggg ggatggagct gagctcatat gggataagga tgacccatct gcaatggatt ttgtcacctc tgctgcaaac ctcaggatgc atattttcag tatgaatatg aagagtagat ttgatatcaa atcaatggca gggaacatta ttcctgctat tgctactact aatgcagtaa ttgctgggtt gatagtattg gaaggattga agattttatc aggaaaaata gaccagtgca gaacaatttt tttgaataaa caaccaaacc caagaaagaa gcttcttgtg ccttgtgcac tggatcctcc caaccccaat tgttatgtat gtgccagcaa gccagaggtg actgtgcggc tgaatgtcca taaagtgact gttctcacct tacaagacaa gatagtgaaa gaaaaatttg ctatggtagc accagatgtc caaattgaag atgggaaagg aacaatccta atatcttccg aagagggaga gacggaagct aataatcaca agaagttgtc agaatttgga attagaaatg gcagccggct tcaagcagat gacttcctcc aggactatac tttattgatc aacatccttc atagtgaaga cctaggaaag gacgttgaat ttgaagttgt tggtgatgcc ccggaaaaag tggggcccaa acaagctgaa gatgctgcca aaagcataac caatggcagt gatgatggag ctcagccctc cacctccaca gctcaagagc aagatgacgt tctcatagtt gattcggatg aagaagattc ttcaaataat gccgacgtca gtgaagaaga gagaagccgc aagaggaaat tagatgagaa agagaatctc agtgcaaaga ggtcacgtat agaacagaag gaagagcttg atgatgtcat agcattagat tga. It is sometimes possible for the material contained within the vial of "UBA2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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