AGTPBP1 cdna clone
AGTPBP1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
NNA1 is a zinc carboxypeptidase that contains nuclear localization signals and an ATP/GTP-binding motif that was initially cloned from regenerating spinal cord neurons of the mouse.[supplied by OMIM, Jul 2002]
Uniprot Description
Nna1: Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Interacts with MYLK. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.17.-; Protease
Chromosomal Location of Human Ortholog: 9q21.33
Cellular Component: cytoplasm; cytosol; mitochondrion; nucleus
Molecular Function: metallocarboxypeptidase activity; tubulin binding
Biological Process: cerebellar Purkinje cell differentiation; eye photoreceptor cell differentiation; mitochondrion organization and biogenesis; neuromuscular process; olfactory bulb development
Research Articles on AGTPBP1
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Product Notes
The AGTPBP1 agtpbp1 (Catalog #AAA1274387) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagcaagt taaaagtgat accagaaaaa agccttacca ataattctag gatcgtagga ctcctggctc aactggagaa gatcaatgct gagccttcag aatcagacac tgcccgatat gttacatcaa aaattcttca tctggctcag agtcaagaaa aaacaaggag agaaatgaca gccaaaggtt ctacaggaat ggaaattctg ctgtcaacat tagagaacac aaaagatctt caaactacac ttaatatctt aagcattctt gttgagctgg tgtcagctgg tggaggtcga agagtgagtt tcttagtcac caaaggtggt tcacaaatat tgttgcagtt acttatgaat gccagcaaag aatctccccc acatgaggac ttaatggtac agattcattc tattcttgca aagattggac caaaagataa aaaatttgga gtaaaggcta gaattaatgg ggctctgaat ataaccctga atttggtcaa gcagaatttg cagaatcatc gcttggttct accttgcctt cagcttttac gagtatattc tgccaactct gtgaattcag tatccttagg gaaaaatgga gttgtggaac tgatgtttaa aatcattgga ccatttagta agaagaattc cagtcttata aaggttgctt tagacactct tgctgcattg ctaaaatcaa aaacaaatgc caggagagct gtagacagag gatatgtcca agtgctttta acaatttatg tagattggca ccgccatgat aaccggcata gaaacatgct cattcggaaa ggaattttac agagtttaaa aagtgttaca aacatcaagt tgggaagaaa agcatttatt gatgccaatg ggatgaaaat tctgtataat acttcgcaat tgcctgttat tcctgtgact ggtcctgtgg ctcagctcta cagcttacct cctgaagtgg atgacgtagt agatgaaagt gatgacaacg atgatattga tgtagaagct gaaaacgaaa ctgagaatga agatgaccta gatcaaaatt ttaagaatga tgatattgaa acagatatta acaaactaaa accccagcaa gaaccgggac gaacaataga agatctaaaa atgtatgaac accttttccc tgagcttgtt gatgattttc aggactatga tttaatctcc aaagaaccaa agccttttgt atttgaggga aaagtacgtg gtcctattgt tgttcctacg gcaggcgagg aaacatctgg gaattctggc aatttaagaa aagttgtaat gaaggagaac atatcttcta aaggagatga aggtgaaaag aagtctacct ttatggatct agcaaaagaa gatattaaag ataatgatag aacattacaa cagcagccag gtgatcaaaa tagaactatt tcatcagtcc atggtttaaa caatgatatt gtaaaggcct tggaccgaat tacattgcag aatattcctt ctcaaacagc cccaggtttt actgcagaaa tgaagaagga ctgcagtctt cctcttactg tccttacctg tgctaaagca tgtccacaca tggctacttg tggaaatgtt ctgtttgagg gaagaacagt tcagctaggg aagctttgct gcactggagt tgaaactgaa gatgatgaag atactgagtc aaattcatcg gtagaacaag catcggttga agtacctgat ggaccaacac tccatgaccc agacctctat attgagattg tgaaaaatac gaagtctgtc ccagaatatt cagaggtggc ttatcccgat tattttggtc acattccgcc tccattcaaa gagcctattt tagaaaggcc ttatggtgta caaaggacaa aaattgctca agatattgaa aggctaatac atcagagtga tatcatagat cgtgtggtat atgacttgga taacccaaat tacaccattc cagaagaggg agatattttg aaatttaact ccaaatttga gtctgggaat ctgcgcaaag taattcaaat tagaaaaaat gaatatgatc ttattctgaa ctcagacata aacagcaatc attatcatca gtggttttac tttgaagtca gtggaatgcg accaggtgtt gcttacaggt ttaacatcat taactgtgaa aagtccaaca gtcagtttaa ttatggtatg caaccactca tgtattcggt tcaggaagca ttaaatgcca gaccatggtg gattcgtatg gggactgaca tttgttacta taaaaatcat ttctcaagaa gttcagttgc tgcaggtggg caaaagggaa aatcctacta tacaattaca tttactgtca attttccaca taaagatgat gtttgctact ttgcttatca ctatccatat acgtattcaa ctttacagat gcatcttcaa aaattggaat cagcacacaa tcctcagcaa atctattttc ggaaagatgt gttatgtgaa accctgtctg gaaacagctg ccccttggtg actataacag caatgccaga gtctaattat tatgaacata tctgccattt cagaaatcgc ccttacgttt tcttgtctgc tcgggtacat cctggagaaa ctaatgcaag ttgggttatg aaaggaacgt tggaatatct catgagcaat aaccccactg ctcagagctt acgagaatct tatattttta aaattgtccc tatgttaaat ccagatggtg tcatcaatgg aaatcatcgc tgttctttaa gtggagagga tttgaatagg cagtggcaaa gtccaagtcc ggatttacat cctacaattt accatgctaa ggggctgttg caatacttgg ctgcagtgaa gcgtttaccc ttggtttatt gtgattatca tggccattcc cgaaagaaga atgtatttat gtatggttgc agcatcaaag agacagtgtg gcataccaat gataatgcaa cttcatgtga tgttgtggag gatacgggat acaggacatt gcctaagata ctgagccata tcgccccagc attttgcatg agcagctgta gcttcgtagt ggaaaaatct aaagaatcca cagcacgtgt tgtagtttgg agggaaatag gagtacaaag aagttatacc atggagagta ctttatgtgg ctgtgatcag ggaaaataca agggtttaca gattggtacc cgagaactgg aagagatggg agcaaaattt tgtgttggtc ttttacgttt gaaaagactg acctctccat tggagtataa tctgccttcc agcctgcttg actttgaaaa tgatttaatt gaatcaagct gcaaagtaac tagccctacc acttatgtct tggatgaaga tgaacctcga ttccttgaag aagttgatta cagtgcagaa agtaatgatg agttagatat tgagttggct gaaaatgtag gagattatga accttctgct caagaagaag tactttctga ctctgaatta tcaagaacat acctaccttg a. It is sometimes possible for the material contained within the vial of "AGTPBP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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