IL3 cdna clone
IL3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
Uniprot Description
IL3: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family.
Protein type: Secreted, signal peptide; Secreted; Apoptosis; Cytokine; Cell cycle regulation; Oncoprotein
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity; interleukin-3 receptor binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity
Biological Process: cell-cell signaling; cytokine and chemokine mediated signaling pathway; embryonic hemopoiesis; MAPKKK cascade; nervous system development; positive regulation of cell proliferation; positive regulation of DNA replication; positive regulation of myeloid leukocyte differentiation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of tyrosine phosphorylation of Stat5 protein
Research Articles on IL3
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Product Notes
The IL3 il3 (Catalog #AAA1273791) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagccgcc tgcccgtcct gctcctgctc caactcctgg tccgccccgg actccaagct cccatgaccc agacaacgcc cttgaagaca agctgggtta actgctctaa catgatcgat gaaattataa cacacttaaa gcagccacct ttgcctttgc tggacttcaa caacctcaat ggggaagacc aagacattct gatggaaaat aaccttcgaa ggccaaacct ggaggcattc aacagggctg tcaagagttt acagaacgca tcagcaattg agagcattct taaaaatctc ctgccatgtc tgcccctggc cacggccgca cccacgcgac atccaatcca tatcaaggac ggtgactgga atgaattccg gaggaaactg acgttctatc tgaaaaccct tgagaatgcg caggctcaac agacgacttt gagcctcgcg atcttttga. It is sometimes possible for the material contained within the vial of "IL3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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