AKR1B10 cdna clone
AKR1B10 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family.
Protein type: EC 1.1.1.-; Carbohydrate Metabolism - fructose and mannose; EC 1.1.1.21; Lipid Metabolism - linoleic acid; Carbohydrate Metabolism - butanoate; Oxidoreductase
Chromosomal Location of Human Ortholog: 7q33
Cellular Component: cytosol
Molecular Function: aldo-keto reductase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; protein binding; retinal dehydrogenase activity
Biological Process: aldehyde metabolic process; digestion; farnesol catabolic process; retinoid metabolic process; steroid metabolic process
Research Articles on AKR1B10
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Product Notes
The AKR1B10 akr1b10 (Catalog #AAA1273450) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggccacgt ttgtggagct cagtaccaaa gccaagatgc ccattgtggg cctgggcact tggaagtctc ctcttggcaa agtgaaagaa gcagtgaagg tggccattga tgcaggatat cggcacattg actgtgccta tgtctatcag aatgaacatg aagtggggga agccatccaa gagaagatcc aagagaaggc tgtgaagcgg gaggacctgt tcatcgtcag caagttgtgg cccactttct ttgagagacc ccttgtgagg aaagcctttg agaagaccct caaggacctg aagctgagct atctggacgt ctatcttatt cactggccac agggattcaa gtctggggat gaccttttcc ccaaagatga taaaggtaat gccatcggtg gaaaagcaac gttcttggat gcctgggagg ccatggagga gctggtggat gaggggctgg tgaaagccct tggggtctcc aatttcagcc acttccagat cgagaagctc ttgaacaaac ctggactgaa atataaacca gtgactaacc aggttgagtg tcacccatac ctcacacagg agaaactgat ccagtactgc cactccaagg gcatcaccgt tacggcctac agccccctgg gctctccgga tagaccttgg gccaagccag aagacccttc cctgctggag gatcccaaga ttaaggagat tgctgcaaag cacaaaaaaa ccgcagccca ggttctgatc cgtttccata tccagaggaa tgtgattgtc atccccaagt ctgtgacacc agcacgcatt gttgagaaca ttcaggtctt tgactttaaa ttgagtgatg aggagatggc aaccatactc agcttcaaca gaaactggag ggcctgtaac gtgttgcaat cctctcattt ggaagactat cccttcgatg cagaatattg a. It is sometimes possible for the material contained within the vial of "AKR1B10, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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