STRC cdna clone
STRC cDNA Clone
Gene Names
STRC; DFNB16
Synonyms
STRC; STRC cDNA Clone; STRC cdna clone
Sequence
ATGGAGCTGCTGGCCTGCTTTAGTCCTGTGCTGTGGGATCTGCTCCAGAGGGAAAAGAGTGTTTGGGCCCTGCAGATTCTAGTGCAGGCGTACCTGCATATGCCCCCAGAAAACCTCCAGCAGCTGGTGCTTTCAGCAGAGAGGGAGGCTGCACAGGGCTTCCTGACACTCATGCTGCAGGGGAAGCTGCAGGGGAAGCTGCAGGTACCACCATCCGAGGAGCAGGCCCTGGGTCGCCTGACAGCCCTGCTGCTCCAGCGGTACCCACGCCTCACCTCCCAGCTCTTCATTGACCTGTCACCACTCATCCCTTTCTTGGCTGTCTCTGACCTGATGCGCTTCCCACCATCCCTGTTAGCCAACGACAGTGTACAGCAGGGCTACAGAGGGTCAGAGGAAAACAGTTTGGAGGAAGACAAAGGGTTAAGACCCATGACTCCTCGCAGCCTGGCTGCCATCCGGGATTACAGCCCAGGAATGAGGCCTGAACAGAAGGAGGCTCTGGCAAAGCGACTGCTGGCCCCTGAACTGTTTGGGGAAGTGCCTGCCTGGCCCCAGGAGCTGCTGTGGGCAGTGCTGCCCCTGCTCCCCCACCTCCCTCTGGAGAACTTTTTGCAGCTCAGCCCTCACCAGATCCAGGCCCTGGAGGATAGCTGGCCAGCAGCAGGTCTGGGGCCAGGGCATGCCCGCCATGTGCTGCGCAGCCTGGTAAACCAGAGTGTCCAGGATGGTGAGGAGCAGGTACGCAGGCTTGGGCCCCTCGCCTGTTTCCTGAGCCCTGAGGAGCTGCAGAGCCTAGTGCCCCTGAGTGATCCAACGGGGCCAGTAGAACGGGGGCTGCTGGAATGTGCAGCCAATGGGACCCTCAGCCCAGAAGGACGGGTGGCATATGAACTTCTGGGTGTGTTGCGCTCATCTGGAGGAGCGGTGCTGAGCCCCCGGGAGCTGCGGGTCTGGGCCCCTCTCTTCTCTCAGCTGGGCCTCCGCTTCCTTCAGGAGCTGTCAGAGCCCCAGCTTAGAGCCATGCTTCCTGTCCTGCAGGGAACTAGTGTTACACCTGCTCAGGCTGTCCTGCTGCTTGGACGGCTCCTTCCTAGGCACGATCTGCTACAACTGGATTCCTTGGCTCTTCTGGCAAATCGAAGACGCTACTGGGAGCTGCCCTGGTCTGAGCAGCAGGCACAGTTTCTCTGGAAGAAGATGCAAGTACCCACCAACCTTACCCTCAGGAATCTGCAGGCTCTGGGCACCCTGGCAGGAGGCATGTCCTGTGAGTTTCTGCAGCAGATCAACTCCATGGTAGACTTCCTTGAAGTGGTGCACATGATCTATCAGCTGCCCACTAGAGTTCGAGGGAGCCTGAGGGCCTGTATCTGGGCAGAGCTACAGCGGAGGATGGCAATGCCAGAACCAGAATGGACAACTGTAGGGCCAGAACTGAACGGGCTGGATAGCAAGCTACTCCTGGACTTACCGATCCAGTTGATGGACAGACTATCCAATGAATCCATTATGTTGGTGGTGGAGCTGGTGCAAAGAGCTCCAGAGCAGCTGCTGGCACTGACCCCCCTCCACCAGGCAGCCCTGGCAGAGAGGGCACTACAAAACCTGGCTCCAAAGGAGACTCCAGTCTCAGGGGAAGTGCTGGAGACCTTAGGCCCTTTGGTTGGATTCCTGGGGACAGAGAGCACACGACAGATCCCCCTACAGATCCTGCTGTCCCATCTCAGTCAGCTGCAAGGCTTCTGCCTAGGAGAGACATTTGCCACAGAGCTGGGATGGCTGCTATTGCAGGAGTCTGTTCTTGGGAAACCAGAGTTGTGGAGCCAGGATGAAGTAGAGCAAGCTGGACGCCTAGTATTCACTCTGTCTACTGAGGCAATTTCCTTGATCCCCAGGGAGGCCTTGGGTCCAGAGACCCTGGAGCGGCTTCTAGAAAAGCAGCAGAGCTGGGAGCAGAGCAGAGTTGGACAGCTGTGTAGGGAGCCACAGCTTGCTGCCAAGAAAGCAGCCCTGGTAGCAGGGGTGGTGCGACCAGCTGCTGAGGATCTTCCAGAACCTGTGCCAAATTGTGCAGATGTACGAGGGACATTCCCAGCAGCCTGGTCTGCAACCCAGATTGCAGAGATGGAGCTCTCAGACTTTGAGGACTGCCTGACATTATTTGCAGGAGACCCAGGACTTGGGCCTGAGGAACTGCGGGCAGCCATGGGCAAAGCAAAACAGTTGTGGGGTCCCCCCCAGGGATTTCGTCCTGAGCAGATCCTGCAGCTTGGTAGGCTCTTAATAGGTCTAGGAGATCGGGAACTACAGGAGCTGATCCTAGTGGACTGGGGAGTGCTGAGCACCCTGGGGCAGATAGATGGCTGGAGCACCACTCAGCTCCGCATTGTGGTCTCCAGTTTCCTACGGCAGAGTGGTCGGCATGTGAGCCACCTGGACTTCGTTCATCTGACAGCGCTGGGTTATACTCTCTGTGGACTGCGGCCAGAGGAGCTCCAGCACATCAGCAGTTGGGAGTTCAGCCAAGCAGCTCTCTTCCTCGGCACCCTGCATCTCCAGTGCTCTGAGGAACAACTGGAGGTTCTGGCCCACCTACTTGTACTGCCTGGTGGGTTTGGCCCAATCAGTAACTGGGGGCCTGAGATCTTCACTGAAATTGGCACCATAGCAGCTGGGATCCCAGACCTGGCTCTTTCAGCACTGCTGCGGGGACAGATCCAGGGCGTTACTCCTCTTGCCATTTCTGTCATCCCTCCTCCTAAATTTGCTGTGGTGTTTAGTCCCATCCAACTATCTAGTCTCACCAGTGCTCAGGCTGTGGCTGTCACTCCTGAGCAAATGGCCTTTCTGAGTCCTGAGCAGCGACGAGCAGTTGCATGGGCCCAACATGAGGGAAAGGAGAGCCCAGAACAGCAAGGTCGAAGTACAGCCTGGGGCCTCCAGGACTGGTCACGACCTTCCTGGTCCCTGGTATTGACTATCAGCTTCCTTGGCCACCTGCTATGA
Sequence Length
3009
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
192,967 Da
NCBI Official Full Name
Homo sapiens stereocilin, mRNA
NCBI Official Synonym Full Names
stereocilin
NCBI Official Symbol
STRC
NCBI Official Synonym Symbols
DFNB16
NCBI Protein Information
stereocilin
UniProt Protein Name
Stereocilin
Protein Family
UniProt Gene Name
STRC
UniProt Entry Name
STRC_HUMAN
NCBI Description
This gene encodes a protein that is associated with the hair bundle of the sensory hair cells in the inner ear. The hair bundle is composed of stiff microvilli called stereocilia and is involved with mechanoreception of sound waves. This gene is part of a tandem duplication on chromosome 15; the second copy is a pseudogene. Mutations in this gene cause autosomal recessive non-syndromic deafness. [provided by RefSeq, Jul 2008]
Uniprot Description
STRC: Essential to the formation of horizontal top connectors between outer hair cell stereocilia. Defects in STRC are the cause of deafness autosomal recessive type 16 (DFNB16). DFNB16 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. Defects in STRC are a cause of deafness-infertility syndrome (DIS). DIS is characterized by deafness and infertility and is caused by large contiguous gene deletions at 15q15.3 that removes both STRC and CATSPER2 genes. Belongs to the stereocilin family.
Chromosomal Location of Human Ortholog: 15q15.3
Cellular Component: cell surface; stereocilium bundle tip
Biological Process: auditory receptor cell stereocilium organization and biogenesis; cell-matrix adhesion; sensory perception of sound
Disease: Deafness, Autosomal Recessive 16; Deafness, Sensorineural, And Male Infertility; Spermatogenic Failure 7
Research Articles on STRC
Similar Products
Product Notes
The STRC strc (Catalog #AAA1271994) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGAGCTGC TGGCCTGCTT TAGTCCTGTG CTGTGGGATC TGCTCCAGAG GGAAAAGAGT GTTTGGGCCC TGCAGATTCT AGTGCAGGCG TACCTGCATA TGCCCCCAGA AAACCTCCAG CAGCTGGTGC TTTCAGCAGA GAGGGAGGCT GCACAGGGCT TCCTGACACT CATGCTGCAG GGGAAGCTGC AGGGGAAGCT GCAGGTACCA CCATCCGAGG AGCAGGCCCT GGGTCGCCTG ACAGCCCTGC TGCTCCAGCG GTACCCACGC CTCACCTCCC AGCTCTTCAT TGACCTGTCA CCACTCATCC CTTTCTTGGC TGTCTCTGAC CTGATGCGCT TCCCACCATC CCTGTTAGCC AACGACAGTG TACAGCAGGG CTACAGAGGG TCAGAGGAAA ACAGTTTGGA GGAAGACAAA GGGTTAAGAC CCATGACTCC TCGCAGCCTG GCTGCCATCC GGGATTACAG CCCAGGAATG AGGCCTGAAC AGAAGGAGGC TCTGGCAAAG CGACTGCTGG CCCCTGAACT GTTTGGGGAA GTGCCTGCCT GGCCCCAGGA GCTGCTGTGG GCAGTGCTGC CCCTGCTCCC CCACCTCCCT CTGGAGAACT TTTTGCAGCT CAGCCCTCAC CAGATCCAGG CCCTGGAGGA TAGCTGGCCA GCAGCAGGTC TGGGGCCAGG GCATGCCCGC CATGTGCTGC GCAGCCTGGT AAACCAGAGT GTCCAGGATG GTGAGGAGCA GGTACGCAGG CTTGGGCCCC TCGCCTGTTT CCTGAGCCCT GAGGAGCTGC AGAGCCTAGT GCCCCTGAGT GATCCAACGG GGCCAGTAGA ACGGGGGCTG CTGGAATGTG CAGCCAATGG GACCCTCAGC CCAGAAGGAC GGGTGGCATA TGAACTTCTG GGTGTGTTGC GCTCATCTGG AGGAGCGGTG CTGAGCCCCC GGGAGCTGCG GGTCTGGGCC CCTCTCTTCT CTCAGCTGGG CCTCCGCTTC CTTCAGGAGC TGTCAGAGCC CCAGCTTAGA GCCATGCTTC CTGTCCTGCA GGGAACTAGT GTTACACCTG CTCAGGCTGT CCTGCTGCTT GGACGGCTCC TTCCTAGGCA CGATCTGCTA CAACTGGATT CCTTGGCTCT TCTGGCAAAT CGAAGACGCT ACTGGGAGCT GCCCTGGTCT GAGCAGCAGG CACAGTTTCT CTGGAAGAAG ATGCAAGTAC CCACCAACCT TACCCTCAGG AATCTGCAGG CTCTGGGCAC CCTGGCAGGA GGCATGTCCT GTGAGTTTCT GCAGCAGATC AACTCCATGG TAGACTTCCT TGAAGTGGTG CACATGATCT ATCAGCTGCC CACTAGAGTT CGAGGGAGCC TGAGGGCCTG TATCTGGGCA GAGCTACAGC GGAGGATGGC AATGCCAGAA CCAGAATGGA CAACTGTAGG GCCAGAACTG AACGGGCTGG ATAGCAAGCT ACTCCTGGAC TTACCGATCC AGTTGATGGA CAGACTATCC AATGAATCCA TTATGTTGGT GGTGGAGCTG GTGCAAAGAG CTCCAGAGCA GCTGCTGGCA CTGACCCCCC TCCACCAGGC AGCCCTGGCA GAGAGGGCAC TACAAAACCT GGCTCCAAAG GAGACTCCAG TCTCAGGGGA AGTGCTGGAG ACCTTAGGCC CTTTGGTTGG ATTCCTGGGG ACAGAGAGCA CACGACAGAT CCCCCTACAG ATCCTGCTGT CCCATCTCAG TCAGCTGCAA GGCTTCTGCC TAGGAGAGAC ATTTGCCACA GAGCTGGGAT GGCTGCTATT GCAGGAGTCT GTTCTTGGGA AACCAGAGTT GTGGAGCCAG GATGAAGTAG AGCAAGCTGG ACGCCTAGTA TTCACTCTGT CTACTGAGGC AATTTCCTTG ATCCCCAGGG AGGCCTTGGG TCCAGAGACC CTGGAGCGGC TTCTAGAAAA GCAGCAGAGC TGGGAGCAGA GCAGAGTTGG ACAGCTGTGT AGGGAGCCAC AGCTTGCTGC CAAGAAAGCA GCCCTGGTAG CAGGGGTGGT GCGACCAGCT GCTGAGGATC TTCCAGAACC TGTGCCAAAT TGTGCAGATG TACGAGGGAC ATTCCCAGCA GCCTGGTCTG CAACCCAGAT TGCAGAGATG GAGCTCTCAG ACTTTGAGGA CTGCCTGACA TTATTTGCAG GAGACCCAGG ACTTGGGCCT GAGGAACTGC GGGCAGCCAT GGGCAAAGCA AAACAGTTGT GGGGTCCCCC CCAGGGATTT CGTCCTGAGC AGATCCTGCA GCTTGGTAGG CTCTTAATAG GTCTAGGAGA TCGGGAACTA CAGGAGCTGA TCCTAGTGGA CTGGGGAGTG CTGAGCACCC TGGGGCAGAT AGATGGCTGG AGCACCACTC AGCTCCGCAT TGTGGTCTCC AGTTTCCTAC GGCAGAGTGG TCGGCATGTG AGCCACCTGG ACTTCGTTCA TCTGACAGCG CTGGGTTATA CTCTCTGTGG ACTGCGGCCA GAGGAGCTCC AGCACATCAG CAGTTGGGAG TTCAGCCAAG CAGCTCTCTT CCTCGGCACC CTGCATCTCC AGTGCTCTGA GGAACAACTG GAGGTTCTGG CCCACCTACT TGTACTGCCT GGTGGGTTTG GCCCAATCAG TAACTGGGGG CCTGAGATCT TCACTGAAAT TGGCACCATA GCAGCTGGGA TCCCAGACCT GGCTCTTTCA GCACTGCTGC GGGGACAGAT CCAGGGCGTT ACTCCTCTTG CCATTTCTGT CATCCCTCCT CCTAAATTTG CTGTGGTGTT TAGTCCCATC CAACTATCTA GTCTCACCAG TGCTCAGGCT GTGGCTGTCA CTCCTGAGCA AATGGCCTTT CTGAGTCCTG AGCAGCGACG AGCAGTTGCA TGGGCCCAAC ATGAGGGAAA GGAGAGCCCA GAACAGCAAG GTCGAAGTAC AGCCTGGGGC CTCCAGGACT GGTCACGACC TTCCTGGTCC CTGGTATTGA CTATCAGCTT CCTTGGCCAC CTGCTATGA. It is sometimes possible for the material contained within the vial of "STRC, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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