USP48 cdna clone
USP48 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
USP48: Recognizes and hydrolyzes the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly- ubiquitin precursors as well as that of ubiquitinated proteins. May be involved in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. Belongs to the peptidase C19 family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin-specific protease; Protease; Ubiquitin conjugating system; EC 3.4.19.12
Chromosomal Location of Human Ortholog: 1p36.12
Cellular Component: cytoplasm; mitochondrion; nucleoplasm
Research Articles on USP48
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Product Notes
The USP48 usp48 (Catalog #AAA1270332) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtttacat ttgcttccat gaccaaagaa gattctaaac ttatagctct catatggccc agtgagtggc aaatgataca aaagctcttt gttgtggatc atgtaattaa aatcacgaga attgaagtgg gagatgtaaa cccttcagaa acacagtata tttctgagcc caaactctgt ccagaatgca gagaaggctt attgtgtcag cagcagaggg acctgcgtga atacactcaa gccaccatct atgtccataa agttgtggat aataaaaagg tgatgaagga ttcggctccg gaactgaatg tgagtagttc tgaaacagag gaggacaagg aagaagctaa accagatgga gaaaaagatc cagattttaa tcaaagcaat ggtggaacaa agcggcaaaa gatatcccat caaaattata tagcctatca aaagcaagtt attcgccgaa gtatgcgaca tagaaaagtt cgtggtgaga aagcacttct cgtttctgct aatcagacgt taaaagaatt gaaaattcag atcatgcatg cattttcagt tgctcctttt gaccagaatt tgtcaattga tggaaagatt ttaagtgatg actgtgccac cctaggcacc cttggcgtca ttcctgaatc tgtcatttta ttgaaggctg atgaaccaat tgcagattat gctgcaatgg atgatgtcat gcaagtttgt atgccagaag aagggtttaa aggtactggt cttcttggac attaa. It is sometimes possible for the material contained within the vial of "USP48, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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