RAD54B cdna clone
RAD54B cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]
Uniprot Description
RAD54B: Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group. Belongs to the SNF2/RAD54 helicase family.
Protein type: DNA repair, damage; EC 3.6.1.-; EC 3.6.4.-; Helicase
Chromosomal Location of Human Ortholog: 8q22.1
Molecular Function: DNA helicase activity; DNA translocase activity; protein binding; RNA helicase activity
Biological Process: double-strand break repair via homologous recombination; meiotic recombination; mitotic recombination
Disease: Lymphoma, Non-hodgkin, Familial
Research Articles on RAD54B
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Product Notes
The RAD54B rad54b (Catalog #AAA1270246) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagacgat ctgcagcacc aagtcagttg caggggaatt ccttcaaaaa accaaaattt atacctccag gaagaagtaa tccaggtctg aatgaagaga ttacaaaact gaatccagat ataaaattat ttgagggtgt tgcaattaat aacacctttc tcccgtcaca aaatgatctt agaatatgca gtttaaatct gcctagtgaa gaaagtacta gagaaatcaa taacagagat aattgcagtg gaaaatattg ttttgaagca cctacactgg caacattaga tccacctcat acagttcatt cggctcctaa agaagtagca gtgtccaagg aacaagaaga gaaatctgat agcctagtta aatatttcag tgttgtttgg tgtaagcctt caaagaaaaa acataaaaag tgggaaggtg atgctgttct tattgtaaaa ggaaagtcat ttatattaaa gaatttggaa ggcaaagaca ttggaagagg cattggttat aaattcaaag agcttgaaaa gattgaagag ggccaaacac tgatgatttg tggaaaagaa atagaagtca tgggtgtaat ctctccagat gacttcagca gtggcaggtg ttttcagctt ggaggaggaa gtactgctat ctcgcattct tctcaggttg ccaggaaatg tttctctaac cctttcaaaa gtgtttgtaa accaagttca aaggaaaata gacagaatga tttccaaaat tgcaaaccac gccatgaccc atatacgcca aattccctcg ttatgccacg accagataag aatcaccagt gggtattcaa taagaactgt ttccctcttg tggatgtagt gattgatcct taccttgtat atcatcttcg accacatcag aaagaaggaa tcatattcct ttatgaatgt gtaatgggaa tgagaatgaa tggcagatgt ggagctattc ttgctgatga aatgggttta gggaagacat tgcaatgtat ttcgctcatc tggaccctgc agtgtcaggg accctatgga ggcaagccag taataaagaa gacactaatt gtcacacctg gaagcttggt gaataattgg aagaaagaat ttcaaaaatg gctaggaagt gaaaggatca agatatttac tgttgatcag gaccacaaag ttgaagaatt catcaagtct atattttatt ctgttcttat tatcagttat gaaatgttac ttcgttccct ggatcaaatt aagaatataa aatttgatct tctaatctgt gacgaggggc atcgtttgaa gaacagtgcc attaagacaa ctacagccct cattagcctt tcttgtgaga aaagaataat tctaactggt actccaattc agaatgatct gcaagaattt tttgcattaa ttgattttgt aaatccagga atattaggct ctttgtcatc ttataggaaa atatatgaag aacccatcat tttatcgaga gaaccttctg cttctgagga agaaaaggag ttaggagaaa gaagagcagc tgaacttact tgcctcactg gactctttat ccttagaaga acccaagaaa ttataaataa atatctccca cctaaaatag agaatgttgt cttttgccga ccaggagcac tacagattga gctttatcga aagctgttaa attctcaggt tgtcaggttc tgccttcaag ggttgttgga aaatagtccc catctaatat gtataggagc tcttaaaaaa ctgtgcaatc acccctgcct tttgttcaac tctataaagg aaaaggaatg tagctcaact tgtgataaaa atgaagaaaa gagtctatac aaaggcttgc taagtgtgtt tcctgctgac tacaaccctc tcctgtttac tgaaaaggag tcaggaaaac tacaggtgtt gtccaagctc ttagcggtta tccacgaact tcgacctact gaaaaggtgg tgttggtatc caactataca caaaccttga acattttaca agaagtatgt aagcgtcatg gatatgctta tacaagactt gatggacaaa caccaatctc tcaaaggcag cagattgttg atggctttaa cagtcaacac tcttcttttt ttattttttt gttaagttca aaagctggtg gtgtaggact taacctcatt ggaggatctc acttaattct ctatgacatt gattggaatc cagccactga cattcaggca atgtctagag tatggagaga tggtcagaaa tatcctgtac atatttacag actcctaact acaggtacaa tagaagaaaa gatctatcaa aggcagatca gtaagcaagg tctttgtggg gcagttgtcg acctcaccaa gacatctgaa catattcagt tttcagtaga agaacttaaa aatttgttca cattacatga aagttcagat tgtgttactc atgatctgct tgactgtgag tgtacaggag aagaagttca tacaggtgat tcgttggaaa aattcattgt ctctagagat tgtcagcttg gtccacatca ccagaaatct aactccctga aacctctttc tatgtcccag ctgaagcaat ggaaacattt ttctggagat catttaaatc ttacagatcc ttttcttgaa agaataacag aaaatgtgtc attcattttt cagaatataa ccactcaagc tactggcaca tag. It is sometimes possible for the material contained within the vial of "RAD54B, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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