USP22 cdna clone
USP22 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
USP22: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression. Belongs to the peptidase C19 family. UBP8 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Protease; EC 3.4.19.12; Ubiquitin-specific protease; Cell cycle regulation; Ubiquitin conjugating system; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 17p11.2
Molecular Function: enzyme binding; H4 histone acetyltransferase activity; ligand-dependent nuclear receptor transcription coactivator activity; protein binding; transcription coactivator activity; ubiquitin-specific protease activity
Biological Process: histone deubiquitination; histone ubiquitination; positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-dependent; protein deubiquitination
Research Articles on USP22
Similar Products
Product Notes
The USP22 usp22 (Catalog #AAA1269880) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCGCCGG GTTGGCCCTC ACTATCAGCG GGCTCCCGAC AGGAGGCGCC CCAGCTTGCG GCCGGGGGCA GCGCCTACCA GGCAGTTGGC AGGCAGTTCC AGCCCCGGGC CACGGCACTG CAGGGCCCGA GCCAGGCCAA GTCCTGTATC TGCCATGTCT GTGGCGTCCA CCTCAACAGG CTGCATTCCT GCCTCTACTG TGTCTTCTTC GGCTGTTTAA CAAAGAAGCA TATTCACGAG CATGCGAAGG CGAAGCGGCA CAACCTGGCC ATTGATCTGA TGTATGGAGG CATCTACTGT TTTCTGTGCC AGGACTACAT CTATGACAAA GACATGGAAA TAATCGCCAA GGAGGAGCAG CGAAAAGCTT GGAAAATGCA AGGCGTTGGA GAGAAGTTTT CAACTTGGGA ACCAACCAAA CGGGAGCTTG AACTGCTGAA GCACAACCCG AAAAGGAGAA AGATCACCTC GAACTGCACC ATAGGTCTGC GTGGGCTGAT CAACCTTGGG AACACATGCT TCATGAACTG CATCGTGCAG GCCCTGACCC ACACGCCACT TCTGCGGGAC TTCTTCCTGT CTGACAGGCA CCGCTGTGAG ATGCAGAGCC CCAGCTCCTG TCTGGTCTGT GAGATGTCCT CACTGTTTCA GGAGTTTTAC TCTGGACACC GGTCCCCTCA CATCCCGTAT AAGTTGCTGC ACCTGGTGTG GACCCACGCG AGGCACCTAG CAGGCTACGA GCAGCAGGAC GCCCACGAGT TCCTCATCGC GGCCCTGGAC GTGCTCCACC GACACTGCAA AGGTGATGAC AATGGGAAGA AGGCCAACAA CCCCAACCAC TGCAACTGCA TCATAGACCA GATCTTCACA GGCGGGTTGC AGTCAGACGT CACCTGCCAA GTCTGCCATG GAGTCTCCAC CACCATCGAC CCCTTCTGGG ACATCAGCTT GGATCTCCCC GGCTCTTCCA CCCCATTCTG GCCCCTGAGC CCAGGGAGCG AGGGCAACGT GGTAAACGGG GAAAGCCACG TGTCGGGAAC CACCACGCTC ACGGACTGCC TGCGACGATT CACCAGACCA GAGCACTTGG GCAGCAGCGC CAAGATCAAG TGCAGCGGTT GCCATAGCTA CCAGGAGTCC ACAAAGCAGC TCACTATGAA GAAACTGCCC ATCGTAGCCT GTTTTCATCT CAAACGATTT GAACACTCAG CCAAGCTGCG GCGGAAGATC ACCACGTATG TGTCCTTCCC CCTGGAGCTG GACATGACCC CTTTCATGGC CTCCAGCAAA GAGAGCAGGA TGAATGGACA GTACCAGCAG CCCACGGACA GTCTCAACAA TGACAACAAG TATTCCCTGT TTGCTGTTGT TAACCATCAA GGGACCTTGG AGAGTGGCCA CTACACCAGC TTTATCCGGC AGCACAAAGA CCAGTGGTTC AAGTGTGACG ATGCCATCAT CACCAAGGCC AGCATCAAGG ACGTCCTGGA CAGCGAAGGG TACTTGCTGT TCTATCACAA ACAGTTCCTG GAATACGAGT AG. It is sometimes possible for the material contained within the vial of "USP22, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.