NCBI Description
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Uniprot Description
GNPDA2: is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Protein type: EC 3.5.99.6; Isomerase; Hydrolase; Carbohydrate Metabolism - amino sugar and nucleotide sugar
Chromosomal Location of Human Ortholog: 4p12
Cellular Component: cytoplasm; cytosol; nucleus
Molecular Function: glucosamine-6-phosphate deaminase activity; protein binding
Biological Process: glucose metabolic process; N-acetylglucosamine catabolic process; N-acetylneuraminate catabolic process; UDP-N-acetylglucosamine biosynthetic process
Product Notes
The GNPDA2 gnpda2 (Catalog #
AAA1269703) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaggcttg taattcttga taactatgac ttggctagtg aatgggcagc caaatacatc tgtaatcgca tcattcagtt caaacctgga caggacagat attttacact gggtttacca acagggagta cacctttagg atgctataaa aaactaatag aatatcataa gaatggacac ctttctttta aatatgtgaa gacctttaat atggatgaat atgtaggact tccaagaaat catcctgaaa gctaccattc ttatatgtgg aataattttt ttaagcatat cgatatagat cctaataatg cacatatcct tgacgggaat gctgcagatt tacaagcaga atgtgatgct tttgaaaaca aaataaaaga agctggagga atagatcttt ttgttggagg aattggtcca gatggtcata tcgctttcaa tgagcctgga tccagtttag tgtcaaggac aagattaaag actctagcaa tggataccat cttggcaaat gccaaatatt ttgatggaga tttatcaaaa gtgtcaacta tggctctaac tgttggtgtg gggacagtga tggatgctag agaagtaatg atccttataa caggggcaca caaggcattt gccctgtaca aagcaataga aggagtcaat cacatgtgga ctgtttccgc tttccagcag catccccgga ctatttttgt atgcgatgaa gatgctactt tagaattaag agttaaaact gtgaaatact ttaaaggtct aatgcatgtg cacaataaac ttgtggatcc actattcagt atgaaagatg gaaactga.
It is sometimes possible for the material contained within the vial of
"GNPDA2, cDNA Clone" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
details on this or any of our
other policies, please see our
Terms & Conditions page.