PTPN23 cdna clone
PTPN23 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the non-receptor type protein-tyrosine phosphatase family. The encoded protein may be involved in the regulation of small nuclear ribonucleo protein assembly and pre-mRNA splicing by modifying the survival motor neuron (SMN) complex. The encoded protein additionally plays a role in ciliogenesis and is part of endosomal sorting complex required for transport (ESCRT) pathways. This gene may serve a tumor suppressor function. [provided by RefSeq, Jul 2016]
Uniprot Description
PTPN23: May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
Protein type: EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3p21.3
Cellular Component: cytoplasm; early endosome; endosome; nucleoplasm; nucleus
Molecular Function: protein binding; protein kinase binding; protein tyrosine phosphatase activity
Biological Process: ubiquitin-dependent protein catabolic process via the multivesicular body pathway
Research Articles on PTPN23
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Product Notes
The PTPN23 ptpn23 (Catalog #AAA1267594) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGAGGCCG TGCCCCGCAT GCCCATGATC TGGCTGGACC TGAAGGAGGC CGGTGACTTT CACTTCCAGC CAGCTGTGAA GAAGTTTGTC CTGAAGAATT ATGGAGAGAA CCCAGAAGCC TACAATGAAG AACTGAAGAA GCTGGAGTTG CTCAGACAGA ATGCTGTCCG TGTCCCACGA GACTTTGAGG GCTGTAGTGT CCTCCGCAAG TACCTCGGCC AGCTTCATTA CCTGCAGAGT CGGGTCCCCA TGGGCTCGGG CCAGGAGGCC GCTGTCCCTG TCACCTGGAC AGAGATCTTC TCAGGCAAGT CTGTGGCCCA TGAGGACATC AAGTACGAGC AGGCCTGTAT TCTCTACAAC CTTGGAGCGC TGCACTCCAT GCTGGGGGCC ATGGACAAGC GGGTGTCTGA GGAGGGCATG AAGGTCTCCT GTACCCATTT CCAGTGCGCA GCCGGCGCCT TCGCCTACCT ACGGGAGCAC TTCCCTCAAG CCTACAGCGT CGACATGAGC CGCCAGATCC TTACGCTCAA CGTCAACCTC ATGCTGGGCC AGGCTCAGGA GTGCCTCCTG GAGAAGTCGA TGTTGGACAA CAGGAAGAGC TTTCTGGTGG CCCGCATCAG TGCACAGGTG GTAGATTACT ACAAGGAGGC ATGCCGGGCC TTGGAGAACC CCGACACTGC CTCACTGCTG GGCCGGATCC AGAAGGACTG GAAGAAACTT GTGCAGATGA AGATCTACTA CTTCGCAGCC GTGGCTCATC TGCACATGGG AAAGCAGGCC GAGGAGCAGC AGAAGTTCGG GGAGCGGGTT GCATACTTCC AGAGCGCCCT GGACAAGCTC AATGAAGCCA TCAAGTTGGC CAAGGGCCAG CCTGACACTG TGCAAGACGC GCTTCGCTTC ACTATGGATG TCATTGGGGG AAAGTACAAT TCTGCCAAGA AGGACAACGA CTTCATTTAC CATGAGGCTG TCCCAGCATT GGACACCCTT CAGCCTGTAA AAGGAGCCCC CTTGGTGAAG CCCTTGCCAG TGAACCCCAC AGACCCAGCT GTTACAGGCC CTGACATCTT TGCCAAACTG GTACCCATGG CTGCCCACGA GGCCTCGTCA CTGTACAGTG AGGAGAAGGC CAAGCTGCTC CGGGAGATGA TGGCCAAGAT TGAGGACAAG AATGAGGTCC TGGACCAGTT CATGGATTCA ATGCAGTTGG ATCCCGAGAC GGTGGACAAC CTTGATGCCT ACAGCCACAT CCCACCCCAG CTCATGGAGA AGTGCGCGGC TCTCAGCGTC CGGCCCGACA CTGTCAGGAA CCTTGTACAG TCCATGCAAG TGCTGTCAGG TGTGTTCACG GATGTGGAGG CTTCCCTGAA GGACATCAGA GATCTGTTGG AGGAGGATGA GCTGCTAGAG CAGAAGTTTC AGGAGGCGGT GGGCCAGGCA GGGGCCATCT CCATCACCTC CAAGGCTGAG CTGGCAGAGG TGAGGCGAGA ATGGGCCAAG TACATGGAAG TCCATGAGAA GGCCTCCTTC ACCAACAGTG AGCTGCACCG TGCCATGAAC CTGCACGTCG GCAACCTGCG CCTGCTCAGC GGGCCGCTTG ACCAGGTCCG GGCTGCCCTG CCCACACCGG CCCTCTCCCC AGAGGACAAG GCCGTGCTGC AAAACCTAAA GCGCATCCTG GCTAAGGTGC AGGAGATGCG GGACCAGCGC GTGTCCCTGG AGCAGCAGCT GCGTGAGCTT ATCCAGAAAG ATGACATCAC TGCCTCGCTG GTCACCACAG ACCACTCAGA GATGAAGAAG TTGTTCGAGG AGCAGCTGAA AAAGTATGAC CAGCTGAAGG TGTACCTGGA GCAGAACCTG GCCGCCCAGG ACCGTGTCCT CTGTGCACTG ACAGAGGCCA ACGTGCAGTA CGCAGCCGTG CGGCGGGTAC TCAGCGACTT GGACCAAAAG TGGAACTCCA CGCTGCAGAC CCTGGTGGCC TCGTATGAAG CCTATGAGGA CCTGATGAAG AAGTCGCAGG AGGGCAGGGA CTTCTACGCA GATCTGGAGA GCAAGGTGGC TGCTCTGCTG GAGCGCACGC AGTCCACCTG CCAGGCCCGC GAGGCTGCCC GCCAGCAGCT CCTGGACAGG GAGCTGAAGA AGAAGCCGCC GCCACGGCCC ACAGCCCCAA AGCCGCTGCT GCCCCGCAGG GAGGAGAGTG AGGCAGTGGA AGCAGGAGAC CCCCCTGAGG AGCTGCGCAG CCTCCCCCCT GACATGGTGG CTGGCCCACG ACTGCCTGAC ACCTTCCTGG GAAGTGCCAC CCCGCTCCAC TTTCCTCCCA GCCCCTTCCC CAGCTCCACA GGCCCAGGAC CCCACTATCT CTCAGGCCCC TTGCCCCCTG GTACCTACTC GGGCCCCACC CAGCTGATAC AGCCCAGGGC CCCAGGGCCC CATGCAATGC CCGTAGCACC TGGGCCTGCC CTCTACCCAG CCCCTGCCTA CACACCGGAG CTGGGCCTTG TGCCCCGATC CTCCCCACAG CATGGCGTGG TGAGCAGTCC CTATGTGGGG GTAGGGCCGG CCCCACCAGT TGCAGGTCTC CCCTCGGCCC CACCTCCTCA ATTCTCAGGC CCCGAGTTGG CCATGGCGGT TCGGCCAGCC ACCACCACAG TAGATAGCAT CCAGGCGCCC ATCCCCAGCC ACACAGCCCC ACGGCCAAAC CCCACCCCTG CTCCTCCCCC GCCCTGCTTC CCTGTGCCCC CACCGCAGCC ACTGCCCACG CCTTACACCT ACCCTGCAGG GGCTAAGCAA CCCATCCCAG CACAGCACCA CTTCTCTTCT GGGATCCCCG CAGGTTTTCC AGCCCCAAGG ATTGGGCCCC AGCCCCAGCC CCATCCTCAG CCCCATCCTT CACAAGCGTT TGGGCCTCAG CCCCCACAGC AGCCCCTTCC ACTCCAGCAT CCACATCTCT TCCCACCCCA GGCCCCAGGA CTCCTACCCC CACAATCCCC CTACCCCTAT GCCCCTCAGC CTGGGGTCCT GGGGCAGCCG CCACCCCCCC TACACACCCA GCTCTACCCA GGTCCCGCTC AAGACCCTCT GCCAGCCCAC TCAGGGGCTC TGCCTTTCCC CAGCCCTGGG CCCCCTCAGC CTCCCCATCC CCCACTGGCA TATGGTCCTG CCCCTTCTAC CAGACCCATG GGCCCCCAGG CAGCCCCTCT TACCATTCGA GGGCCCTCGT CTGCTGGCCA GTCCACCCCT AGTCCCCACC TGGTGCCTTC ACCTGCCCCA TCTCCAGGGC CTGGTCCGGT ACCCCCTCGC CCCCCAGCAG CAGAACCACC CCCTTGCCTG CGCCGAGGCG CCGCAGCTGC AGACCTGCTC TCCTCCAGCC CGGAGAGCCA GCATGGCGGC ACTCAGTCTC CTGGGGGTGG GCAGCCCCTG CTGCAGCCCA CCAAGGTGGA TGCAGCTGAG GGTCGTCGGC CGCAGGCCCT GCGGCTGATT GAGCGGGACC CCTATGAACA TCCTGAGAGG CTGCGGCAGT TGCAGCAGGA GCTGGAGGCC TTTCGGGGTC AGCTGGGGGA TGTGGGAGCT CTGGACACTG TCTGGCGAGA GCTGCAAGAT GCGCAGGAAC ATGATGCCCG AGGCCGTTCC ATCGCCATTG CCCGCTGCTA CTCACTGAAG AACCGGCACC AGGATGTCAT GCCCTATGAC AGTAACCGTG TGGTGCTGCG CTCAGGCAAG GATGACTACA TCAATGCCAG CTGCGTGGAG GGGCTCTCCC CATACTGCCC CCCGCTAGTG GCAACCCAGG CCCCACTGCC TGGCACAGCT GCTGACTTCT GGCTCATGGT CCATGAGCAG AAAGTGTCAG TCATTGTCAT GCTGGTTTCT GAGGCTGAGA TGGAGAAGCA AAAAGTGGCA CGCTACTTCC CCACCGAGAG GGGCCAGCCC ATGGTGCACG GTGCCCTGAG CCTGGCATTG AGCAGCGTCC GCAGCACCGA AACCCATGTG GAGCGCGTGC TGAGCCTGCA GTTCCGAGAC CAGAGCCTCA AGCGCTCTCT TGTGCACCTG CACTTCCCCA CTTGGCCTGA GTTAGGCCTG CCCGACAGCC CCAGCAACTT GCTGCGCTTC ATCCAGGAGG TGCACGCACA TTACCTGCAT CAGCGGCCGC TGCACACGCC CATCATTGTG CACTGCAGCT CTGGTGTGGG CCGCACGGGA GCCTTTGCAC TGCTCTATGC AGCTGTGCAG GAGGTGGAGG CTGGGAACGG AATCCCTGAG CTGCCTCAGC TGGTGCGGCG CATGCGGCAG CAGAGAAAGC ACATGCTGCA GGAGAAGCTG CACCTCAGGT TCTGCTATGA GGCAGTGGTG AGACACGTGG AGCAGGTCCT GCAGCGCCAT GGTGTGCCTC CTCCATGCAA ACCCTTGGCC AGTGCAAGCA TCAGCCAGAA GAACCACCTT CCTCAGGACT CCCAGGACCT GGTCCTCGGT GGGGATGTGC CCATCAGCTC CATCCAGGCC ACCATTGCCA AGCTCAGCAT TCGGCCTCCT GGGGGGTTGG AGTCCCCGGT TGCCAGCTTG CCAGGCCCTG CAGAGCCCCC AGGCCTCCCG CCAGCCAGCC TCCCAGAGTC TACCCCAATC CCATCTTCCT CCCCACCCCC CCTTTCCTCC CCACTACCTG AGGCTCCCCA GCCTAAGGAG GAGCCGCCAG TGCCTGAAGC CCCCAGCTCG GGGCCCCCCT CCTCCTCCCT GGAATTGCTG GCCTCCTTGA CCCCAGAGGC CTTCTCCCTG GACAGCTCCC TGCGGGGCAA ACAGCGGATG AGCAAGCATA ACTTTCTGCA GGCCCATAAC GGGCAAGGGC TGCGGGCCAC CCGGCCCTCT GACGACCCCC TCAGCCTTCT GGATCCACTC TGGACACTCA ACAAGACCTG A. It is sometimes possible for the material contained within the vial of "PTPN23, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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