SRP9 cdna clone
SRP9 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
SRP9: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. Belongs to the SRP9 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Translation; RNA-binding
Chromosomal Location of Human Ortholog: 1q42.12
Cellular Component: cytosol; signal recognition particle receptor complex; signal recognition particle, endoplasmic reticulum targeting
Molecular Function: protein binding; RNA binding; signal recognition particle binding
Biological Process: SRP-dependent cotranslational protein targeting to membrane; SRP-dependent cotranslational protein targeting to membrane, translocation