Baculoviral IAP repeat-containing protein 7 (Birc7) Recombinant Protein | Birc7 recombinant protein
Recombinant Mouse Baculoviral IAP repeat-containing protein 7 (Birc7)
NCBI and Uniprot Product Information
Uniprot Description
Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of caspase-3, -7, and -9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1.
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Product Notes
The Birc7 birc7 (Catalog #AAA1252425) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-285, full length protein. The amino acid sequence is listed below: MFSPADLFRA AVFSMGPESR ARDSVRGPEL SHREDGSGRT QEQDKPHCPC NHVLGQDCLD GQILGQLRPL SEEEESSGAA FLGEPAFPEM DSEDLRLASF YDWPSTAGIQ PEPLAAAGFF HTGQQDKVRC FFCYGGLQSW ERGDDPWTEH ARWFPRCQFL LRSKGRDFVE RIQTYTPLLG SWDQREEPED AVSATPSAPA HGSPELLRSR RETQPEDVSE PGAKDVQEQL RQLQEERRCK VCLDRAVSIV FVPCGHFVCT ECAPNLQLCP ICRVPICSCV RTFLS. It is sometimes possible for the material contained within the vial of "Baculoviral IAP repeat-containing protein 7 (Birc7), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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