Zinc finger BED domain-containing protein 1 (ZBED1) Recombinant Protein | ZBED1 recombinant protein

Recombinant Human Zinc finger BED domain-containing protein 1 (ZBED1)

Cat. Num. AAA1239121

• Gene Names: ZBED1; ALTE; DREF; TRAMP; hDREF
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Zinc finger BED domain-containing protein 1 (ZBED1); Recombinant Human Zinc finger BED domain-containing protein 1 (ZBED1); ZBED1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-694, Full length protein
• Sequence: MENKSLESSQTDLKLVAHPRAKSKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKPESSQQPGQDALAVKAGHGYDSKKQQELTAAVLGLICEGLYPASIVDEPTFKVLLKTADPRYELPSRKYISTKAIPEKYGAVREVILKELAEATWCGISTDMWRSENQNRAYVTLAAHFLGLGAPNCLSMGSRCLKTFEVPEENTAETITRVLYEVFIEWGISAKVFGATTNYGKDIVKACSLLDVAVHMPCLGHTFNAGIQQAFQLPKLGALLSRCRKLVEYFQQSAVAMYMLYEKQKQQNVAHCMLVSNRVSWWGSTLAMLQRLKEQQFVIAGVLVEDSNNHHLMLEASEWATIEGLVELLQPFKQVAEMLSASRYPTISMVKPLLHMLLNTTLNIKETDSKELSMAKEVIAKELSKTYQETPEIDMFLNVATFLDPRYKRLPFLSAFERQQVENRVVEEAKGLLDKVKDGGYRPAEDKIFPVPEEPPVKKLMRTSTPPPASVINNMLAEIFCQTGGVEDQEEWHAQVVEELSNFKSQKVLGLNEDPLKWWSDRLALFPLLPKVLQKYWCVTATRVAPERLFGSAANVVSAKRNRLAPAHVDEQVFLYENARSGAEAEPEDQDEGEWGLDQEQVFSLGDGVSGGFFGIRDSSFL
• Sequence Length: 694

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 283806699
• NCBI GeneID: 9189
• NCBI Accession #: NP_001164606.1
• NCBI GenBank Nucleotide #: NM_001171135.1
• UniProt Accession #: O96006; Q96BY4
• Molecular Weight: 78,156 Da
• NCBI Official Full Name: zinc finger BED domain-containing protein 1
• NCBI Official Synonym Full Names: zinc finger BED-type containing 1
• NCBI Official Symbol: ZBED1
• NCBI Official Synonym Symbols: ALTE; DREF; TRAMP; hDREF
• NCBI Protein Information: zinc finger BED domain-containing protein 1
• UniProt Protein Name: Zinc finger BED domain-containing protein 1
• Protein Family: Zinc finger BED domain-containing protein
• UniProt Gene Name: ZBED1
• UniProt Synonym Gene Names: ALTE; DREF; KIAA0785; TRAMP

NCBI Description

This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]

Uniprot Description

Binds to 5'-TGTCG[CT]GA[CT]A-3' DNA elements found in the promoter regions of a number of genes related to cell proliferation. Binds to the histone H1 promoter and stimulates transcription. Was first identified as gene weakly similar to Ac transposable elements, but does not code for any transposase activity.