3 beta-hydroxysteroid dehydrogenase type 5 (Hsd3b5) Recombinant Protein | Hsd3b5 recombinant protein
Recombinant Rat 3 beta-hydroxysteroid dehydrogenase type 5 (Hsd3b5)
NCBI and Uniprot Product Information
NCBI Description
catalyzes the conversion of delta 5-3 beta-hydroxysteroids to delta 4-3-ketosteroids in steroid hormone biosynthesis [RGD, Feb 2006]
Uniprot Description
HSD3B5: The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD V can only catalyze the conversion of dihydrotestosterone to 5 alpha- androstanediol in the presence of the cofactor NADPH. Does not function as a isomerase. Belongs to the 3-beta-HSD family.
Protein type: Membrane protein, integral; EC 1.1.1.-; Oxidoreductase; Mitochondrial
Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; mitochondrial membrane; integral to membrane
Molecular Function: steroid dehydrogenase activity; 3-beta-hydroxy-delta5-steroid dehydrogenase activity; NAD binding; steroid binding
Biological Process: regulation of steroid biosynthetic process; progesterone metabolic process; steroid biosynthetic process
Research Articles on Hsd3b5
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Product Notes
The Hsd3b5 hsd3b5 (Catalog #AAA1230740) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-373. The amino acid sequence is listed below: PGWSCLVTGA GGFLGQRIVQ MLVQEKELQE VRVLYRTFSP KHKEELSKLQ TKAKVTVLRG DIVDAQFLRR ACQGMSVIIH TAAALDIAGF LPRQTILDVN VKGTQLLLDA CVEASVPAFI YSSSTGVAGP NSYKETILND REEEHRESTW SNPYPYSKRM AEKAVLAANG SILKNGGTFH TCALRLPFIY GEESQIISTM VNRALKNNSI IKRHATFSIA NPVYVGNAAW AHILAARGLR DPEKSQSIQG QFYYISDDTP HQSYDDLNYT LSKEWGFCLD SSWSLPLPLL YWLAFLLETV SFLLRPFYNY RPPFNRFMVT ILNSVFTISY KKAQRDLGYE PLVSWEEAKQ KTSEWIGTLV EQHRETLDTK SQ. It is sometimes possible for the material contained within the vial of "3 beta-hydroxysteroid dehydrogenase type 5 (Hsd3b5), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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