Coatomer subunit delta (ARCN1) Recombinant Protein | ARCN1 recombinant protein

Recombinant Bovine Coatomer subunit delta (ARCN1) , partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Coatomer subunit delta (ARCN1); Recombinant Bovine Coatomer subunit delta (ARCN1); partial; ARCN1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 511

• Species: Bovine
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for ARCN1 recombinant protein

This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or trafficking.

NCBI and Uniprot Product Information

• NCBI GI #: 303324570
• NCBI GeneID: 533078
• NCBI Accession #: NP_001181942.1
• NCBI GenBank Nucleotide #: NM_001195013.1
• UniProt Accession #: P53619
• Molecular Weight: 57,274 Da
• NCBI Official Full Name: coatomer subunit delta
• NCBI Official Synonym Full Names: archain 1
• NCBI Official Symbol: ARCN1
• NCBI Protein Information: coatomer subunit delta
• UniProt Protein Name: Coatomer subunit delta
• Protein Family: Coatomer
• UniProt Gene Name: ARCN1
• UniProt Synonym Gene Names: COPD; Delta-COP

Uniprot Description

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors ().