Protein-export membrane protein SecG (secG) Recombinant Protein | secG recombinant protein
Recombinant Escherichia coli Protein-export membrane protein SecG (secG)
NCBI and Uniprot Product Information
NCBI Description
SecYEG complex interacts with SecDFyajC to form a hexameric holocomplex. [More information is available at EcoGene: EG12095]. SecG is an inner membrane protein involved in the Sec protein secretion pathway. [More information is available at EcoCyc: EG12095].
Uniprot Description
Function: Subunit of the protein translocation channel SecYEG. Overexpression of some hybrid proteins has been thought to jam the protein secretion apparatus resulting in cell death; while this may be true it also results in FtsH-mediated degradation of SecY. Treatment with antibiotics that block translation elongation such as chloramphenicol also leads to degradation of SecY and SecE but not SecG.
Subunit structure: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. SecG probably contacts ribosomal protein L23 and/or L29 when the translocation complex is docked with the ribosome.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Post-translational modification: The N-terminus is blocked.
Sequence similarities: Belongs to the SecG family.
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Product Notes
The secG secg (Catalog #AAA1194823) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-110. The amino acid sequence is listed below: MYEALLVVFL IVAIGLVGLI MLQQGKGADM GASFGAGASA TLFGSSGSGN FMTRMTALLA TLFFIISLVL GNINSNKTNK GSEWENLSAP AKTEQTQPAA PAKPTSDIPN. It is sometimes possible for the material contained within the vial of "Protein-export membrane protein SecG (secG), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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