Prostaglandin D2 receptor-like (Ptgdrl) Recombinant Protein | Ptgdrl recombinant protein
Recombinant Rat Prostaglandin D2 receptor-like (Ptgdrl)
NCBI and Uniprot Product Information
NCBI Description
receptor for prostaglandin D2, may play a role in vision, regulation of intraocular pressure, and sleep induction [RGD, Feb 2006]
Uniprot Description
Function: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein
Potential.
Tissue specificity: Strongly expressed in eye and gastrointestinal tract (GIT), moderately in the brain and oviduct and weakly in the epididymis. In the eye, expressed in the epithelium of the iris and ciliary body and in photoreceptor cells of the retina. In the brain, expressed in leptomeninges, choroid plexus and spinal cord (sensory and motor neurons of the dorsal and ventral horns). In the stomach, expressed in the mucous-secreting goblet cells and the columnar epithelium. Expressed in platelets. Ref.1 Ref.2
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Research Articles on Ptgdrl
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Product Notes
The Ptgdrl ptgdrl (Catalog #AAA1177139) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-357. The amino acid sequence is listed below: MNESYRCQAA TWVERGSSAT MGGVLFSAGL LGNLLALVLL ARSGLGSCRP GPLHPPPSVF YVLVCGLTVT HLLGKCLISP MVLAAYAQNR SLKELLPASG NQLCEAFAFL MSFFGLASTL QLLAMALECW LSLGHPFFYQ RHITARRGVL VAPVAGAFSL AFCALPFAGF GKFVQYCPGT WCFIQMIHKK RSFSVIGFSV LYSSLMALLV LATVVCNLGA MSNLYAMHRR QRHHPRRCSR DRAQSGSDYR HGSPNPLEEL DHFVLLALTT VLFTMCSLPL IYRAYYGAFK LVDRADGDSE DLQALRFLSV ISIVDPWIFI IFRTSVFRML FHKAFTRPLI YRNWCSHSWQ TNMESTL. It is sometimes possible for the material contained within the vial of "Prostaglandin D2 receptor-like (Ptgdrl), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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