WD repeat-containing protein 62 (WDR62) Recombinant Protein | WDR62 recombinant protein

Recombinant Human WD repeat-containing protein 62 (WDR62) , partial

• Gene Names: WDR62; MCPH2; C19orf14
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: WD repeat-containing protein 62 (WDR62); Recombinant Human WD repeat-containing protein 62 (WDR62); partial; WDR62 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 1,523

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 145580608
• NCBI GeneID: 284403
• NCBI Accession #: NP_001077430.1
• NCBI GenBank Nucleotide #: NM_001083961.1
• UniProt Accession #: O43379; Q63HP9; Q659D7; Q8NBF7; Q96AD9
• Molecular Weight: 166,511 Da
• NCBI Official Full Name: WD repeat-containing protein 62 isoform 1
• NCBI Official Synonym Full Names: WD repeat domain 62
• NCBI Official Symbol: WDR62
• NCBI Official Synonym Symbols: MCPH2; C19orf14
• NCBI Protein Information: WD repeat-containing protein 62
• UniProt Protein Name: WD repeat-containing protein 62
• Protein Family: WD repeat-containing protein
• UniProt Gene Name: WDR62
• UniProt Synonym Gene Names: C19orf14

NCBI Description

This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]

Uniprot Description

Required for cerebral cortical development. Plays a role in neuronal proliferation and migration (PubMed:20890278, PubMed:20729831). Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806).